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N-羟基琥珀酰亚胺

点击次数:184发布时间:2015/9/14 16:35:18

N-羟基琥珀酰亚胺

更新日期:2015/9/14 16:35:18

所 在 地:中国大陆

产品型号:99%

简单介绍:N-羟基琥珀酰亚胺是瑞尔丰化工的主产品,目前主要向医药企业销售,在华东地区富有盛名,

相关标签:N-羟基琥珀酰亚胺 

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详细内容

CAS: 6066-82-6
分子式: C4H5NO3
分子量: 115.09

中文名称: N-羟基琥珀酰亚胺
N-羟基丁二酰亚胺
羟基丁二酰亚胺
NHS

英文名称: 1-hydroxy-5-pyrrolidinedione
n-hydroxysuccinimide
hydroxysuccinimide

性状描述: 白色结晶粉末,对潮湿敏感,易结块,熔点99-100℃;溶于水,易溶于丙酮、醇和乙酸乙酯,微溶于氯代烃、醚、甲苯和苯。

质量标准:
含量      ≥98.0%
干燥失重    ≤1.0%
熔点范围    95.0℃~98.0℃
游离丁二酰亚胺 ≤1.0%

用途: 该产品及其衍生物是合成肽、抗生素、氨基酸、蛋白质等重要原料。可用于制备活性酯,在肽偶联时抑制其外旋光作用的发生。

  在医药方面用于活化羧基以用于酰胺键的形成。用于合成氨基酸保护剂、半合成卡那霉素B及医药中间体。


品名 CAS号 规格 包装
N,N-二叔丁基碳二亚胺 691-24-7

99%

25kg/桶

N-苄基马来酰亚胺 1631-26-1

98.5%

25kg/桶

S-苄基琥珀酸 3972-36-9

99%

25kg/桶

二甲基氨基丙基乙基碳酰胺 22572-40-3

99%

25kg/桶

N,N-二环己基碳酰亚胺 538-75-0

99%

25kg/桶

N-(2,4,6-三氯苯)马来酰亚胺 13167-25-4

99%

25kg/桶

1,8-萘内酰亚胺 130-00-7

99%

25kg/桶

DSC 74124-79-1

99%

25kg/桶

FMOC-OSU 82911-69-1

99%

25kg/桶

CPOC-OSU 128595-07-3

99%

25kg/桶

2-BrZ-OSU 128611-93-8

99%

25kg/桶

Z-OSU 13139-17-8

99%

25kg/桶

2-ClZ-OSU 65853-65-8

99%

25kg/桶

3,3-环戊烷戊二酰亚胺 1130-32-1

99%

25kg/桶

N-苯基马来酰亚胺 941-69-5

99.5%

25kg/桶

双马来酰亚胺 13676-54-5

98%

25kg/桶

1,8-萘酰亚胺 81-83-4

99%

25kg/桶

丁二酰亚胺 123-56-8

99%

25kg/桶

N-羟基丁二酰亚胺 6066-82-6

99%

25kg/桶

N-碘代丁二酰亚胺 516-12-1

98%

1kg/包

N-氯代丁二酰亚胺 128-09-6

99%

25kg/桶

N-溴代丁二酰亚胺 128-08-5

98.5%

25kg/桶

 N-羟基丁二酰亚胺安全技术说明书( 英文版)
【Product Name】1-Hydroxy-2,5-pyrrolidinedione N-羟基丁二酰亚胺
【Synonyms】1-Hydroxypyrrolidine-2,5-dione
【CAS】6066-82-6
【Formula】C4H5NO3
【Molecular Weight】115.09
【EINECS】228-001-3
【Beilstein/Gmelin】113913
【Beilstein Reference】5-21-09-00498

Physical and Chemical Properties
【Appearance】White.
【Solubility in water】Soluble
【Melting Point】93 - 95
【Boiling Point】363
【Partition Coefficient】-.87

First Aid Measures
【Ingestion】Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
【Inhalation】Remove from exposure to fresh air immediately.
【Skin】Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
【Eyes】Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids.

Handling and Storage
【Storage】Store in a cool, dry place. Keep container closed when not in use.
【Handling】Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation.

Exposure Controls/Personal Protection
【Personal Protection】Eyes: Wear safety glasses and chemical goggles if splashing is possible. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
【Respirators】Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions.
【Exposure Effects】The toxicological properties of this material have not been investigated.

Fire Fighting Measures
【Flash Point】175
【Fire Fighting】Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Accidental Release Measures
【Small spills/leaks】Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal.
Stability and Reactivity
【Disposal Code】3
【Stability】Stable under normal temperatures and pressures.
【Incompatibilities】Strong oxidizing agents - acid chlorides - acid anhydrides - strong bases - moisture.
【Decomposition】Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Transport Information
【HS Code】2925 19 95

Hazards Identification
【EC Risk Phrase】R 5 36/37/38
【EC Safety Phrase】S 26 36

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