人类表皮生长因子

分类抗体

含量≥97 (SDS-PAGE)（％）

产品规格SIGMA E9644-5×0.2MG

CAS62253-63-8

用途范围生物科研

保存温度-20℃

英文名称Epidermal Growth Factor human-EGF human

供应商      上海极威生物科技有限公司

表皮生长因子 人类      

recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture

· 产品编号：E9644

· 中文名称：表皮生长因子 人类

· 英文名称：Epidermal Growth Factor human-EGF human

· 英文别名:EGF LONG® EGF

· CAS号：62253-63-8

· 纯度：≥97% (SDS-PAGE)

· 保存温度：−20 °C

· MDL号：MFCD00132565

订货信息：

产品规格价格(RMB)

· E9644-0.2MG2,999.88元

· E9644-5X0.2MG13,209.30元

注：此价格仅供参考，请以销售价格为准，优惠价请电询。

性能描述

Analysis Note

≥98% SDS-PAGE

Biochem/physiol Actions

Qualified for use as a mitogen for a variety of epidermal ａnd epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular ａnd corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, ａnd SV40-3T3 cells.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline

Application

Qualified for use as a mitogen for a variety of epidermal ａnd epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular ａnd corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, ａnd SV40-3T3 cells.

General description

Epidermal Growth Factor (EGF) is a small mitogenic polypeptide which is present in many mammalian species ａnd is distributed throughout a wide number of tissues ａnd body fluids. Human EGF is identical to β-urogastrone, a polypeptide which was recognized ａnd isolated on the basis of its ability to inhibit gastric acid secretion. EGF is a member of a growth factor family which is characterized by the presence of 6 conserved cysteine motifs that form three disulfide bonds. The location of 3 intrachain disulfide bonds in recombinant human EGF is identical to that of mouse EGF. EGF is structurally homologous to human transforming growth factor-α (TGF-alpha), ａnd both exert their actions through EGF receptors. EGF is homologous to a sequence contained in a 19 kD protein of vaccinia virus, which appears to utilize the EGF receptor to gain entry into cells.

EGF is mitogenic for a variety of epidermal ａnd epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular ａnd corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, ａnd SV40-3T3 cells.

法律信息

LONG 注册商标 Novozymes Gropep Limited

Other Notes

The biological activity of recombinant, human EGF is measured by its ability to stimulate the mouse fibroblast cell line, BALB/3T3. The EC50 is defined as the effective concentration of growth factor that elicits a 50% increase in cell growth in a cell based bioassay.

性质

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