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Recombinant Human FGF-acidic Peprotech细胞因子厂家
点击次数：315发布时间：2016/1/14 9:12:54
更新日期：2022/5/31 10:15:44
所 在 地：中国大陆
产品型号：100-17A
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详细内容
产品编号:
100-17A
别名:
Fibroblast Growth Factor-acidic, FGF-1, HBGF-1, ECGF-beta
描述:
FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth ａnd regeneration of a variety of tissues, by promoting cellular proliferation ａnd differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes ａnd endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant Human FGF-acidic is a 16.8 kDa protein consisting of 141 amino acid residues.
氨基酸序列:
MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
来源:
E.coli
纯度:
Greater than 95% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105units/mg.
Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.5 ng/ml in the presence of 10 μg/ml heparin, corresponding to a specific activity of ≥ 2 x 106units/mg.
Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.5 ng/ml in the presence of 10 μg/ml heparin, corresponding to a specific activity of ≥ 2 x 106units/mg.
交叉反应:
Cow, Mouse, Pig, Rat, Shark, Squid, Human, Hamster, Hagfish, Leech, N/A
研究领域:
原产国:
USA
仅用于研究。不适用于诊断或治疗。
