产品展示
Recombinant Human FGF-basic Peprotech现货直销
点击次数：203发布时间：2016/1/14 9:18:27
更新日期：2022/5/31 10:15:44
所 在 地：中国大陆
产品型号：100-18B
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详细内容
产品编号:
100-18B
别名:
Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin
描述:
FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth ａnd regeneration of a variety of tissues, by promoting cellular proliferation ａnd differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells ａnd endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c ａnd 4. Recombinant Human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues.
氨基酸序列:
AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS
来源:
E.coli
纯度:
Greater than 95% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106units/mg.
Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
交叉反应:
Cow, Dog, Frog, Hamster, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Human + Mouse, Rat + Chicken, Human, Horse, Bacteria, Trout, Chicken, Human + Rat, Leech, N/A, Human + Virus, Mouse + Pig
研究领域:
原产国:
USA
仅用于研究。不适用于诊断或治疗。
