产品展示
Recombinant Human IFN-r Peprotech 细胞因子报价
点击次数：274发布时间：2016/1/14 9:35:04
更新日期：2022/5/31 10:15:44
所 在 地：中国大陆
产品型号：300-02
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详细内容
产品编号:
300-02
别名:
Immune Interferon, type II interferon, T cell interferon, MAF
描述:
IFN-γ is an acid-labile interferon produced by CD4 ａnd CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells, ａnd antigen-recognizing B ａnd T lymphocytes, regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions, including the anti-microbial ａnd anti-tumor responses of macrophages, NK cells, ａnd neutrophils. Human IFN-γ is species-specific ａnd is biologically active only in human ａnd primate cells. Recombinant Human IFN-γ is a 16.8 kDa protein containing 144 amino acid residues.
氨基酸序列:
MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFQGR RASQ
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
Assay #1: Determined by its ability to induce apoptosis in HeLa cells. The expected ED50 for this effect is 5.0-10.0 ng/ml.
Assay #2: The ED50 determined by a cytotoxicity assay using HT-29 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107units/mg.
Assay #2: The ED50 determined by a cytotoxicity assay using HT-29 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107units/mg.
交叉反应:
Monkey, Human, Mouse, Leech, Pig, Human + Bacteria, Mandarin Fish, Fish + Virus, N/A, Human + Mouse
研究领域:
原产国:
USA
仅用于研究。不适用于诊断或治疗。
