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Recombinant Murine VEGF165Peprotech因子北京厂家
点击次数：532发布时间：2016/1/14 10:57:38
更新日期：2022/5/31 10:15:44
所 在 地：中国大陆
产品型号：450-32
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详细内容
产品编号:
450-32
别名:
Vascular Endothelial Growth Factor, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen, VEGF-A
描述:
VEGF is a potent growth ａnd angiogenic cytokine. It stimulates proliferation ａnd survival of endothelial cells, ａnd promotes angiogenesis ａnd vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal ａnd pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis ａnd intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) ａnd the flt4 gene product. Recombinant murine VEGF is a 39.0 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
氨基酸序列:
MAPTTEGEQK SHEVIKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNITMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
生物活性:
Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-5.0 ng/ml.
交叉反应:
Chicken, Human, Rabbit, Rat, Mouse
研究领域:
原产国:
USA
仅用于研究。不适用于诊断或治疗。
