转录组分析显示，71% (n=14005) 的人类基因 (n=19670) 在宫颈癌中表达。与其他癌症相比，108个基因在宫颈癌中的表达水平有所升高。与宫颈癌预后不良相关的基因有223个，与宫颈癌预后良好相关的基因有501个。Atlas Antibodies公司的相关宫颈癌不利（诊断时较高的相对表达水平会显著降低患者的总生存期）和有利（诊断时较高的相对表达水平会显著提高患者的总生存期）预后相关的zui重要基因指标的优质抗体，助力科研。如下表1和2。

表1.Atlas Antibodies公司宫颈癌不良预后相关的具有重要意义的基因指标

cat# 基因名 应用类型

HPA060766 AIG-1, dJ95L4.1, FLJ10485 IHC, ICC-IF

HPA016646 ASL IHC, WB

HPA028496 C1orf74, FLJ25078 IHC, WB, ICC-IF

HPA057179 CXCL8, 3-10C, GCP1, IL-8, NAP1 IHC, WB, ICC-IF

HPA022129 EGLN1, C1orf12, HIFPH2, SM-20 IHC, ICC-IF

HPA046598 ERG, erg-3, p55 IHC

HPA039700 ESD IHC, WB, ICC-IF

HPA006461 FASN, FAS, SDR27X1 IHC, WB, ICC-IF

HPA014033 FUT11, MGC33202 IHC, ICC-IF

HPA011222 GALNT2, GalNAc-T2 IHC, WB, ICC-IF

HPA002642 ITGA5, CD49e, FNRA IHC, WB

HPA036257 LOXL2, WS9-14 ICC-IF

HPA045783 MOCS1, MOCOD IHC, WB, ICC-IF

HPA016997 P4HA2, C-P4Halpha(II) IHC, WB, ICC-IF

HPA073327 PRKCDBP, CAVIN3, HSRBC, MGC20400 ICC-IF

HPA029193 PON2 IHC, WB

HPA043934 SPRYD7, C13orf1、CLLD6 IHC, ICC-IF

HPA024040 SUMF2, DKFZp566I1024 IHC

HPA054334 TAF1A, SL1, TAFI48 IHC, ICC-IF

HPA017019 TGFBI、BIGH3, CDB1, LCD1 IHC, WB

表2.Atlas Antibodies公司宫颈癌预后良好相关的具有重要意义的基因指标

cat# 基因名 应用类型

HPA019649 AKR1A1，ALR, DD3 IHC, WB, ICC-IF

HPA028956 CETN1, CEN1, CETN IHC

HPA041870 DDX49, FLJ10432 IHC, WB

HPA008411 EAF2, BM040, TRAITS, U19 IHC, WB

HPA046960 F8A1, DXS522E, F8A IHC, WB

HPA038602 ISCU, hnifU, IscU, ISU2, NIFUN IHC, ICC-IF

HPA041076 KIF22, Kid, KNSL4, OBP-1, OBP-2 IHC, WB

HPA049240 MEI1, MGC40042, SPATA38 IHC

HPA069056 NCAPH2, 384D8-2, CAP-H2, hCAP-H2 IHC, WB, ICC-IF

HPA041353 NMRAL1, FLJ25918, HSCARG, SDR48A1 IHC, WB, ICC-IF

HPA059740 PLA1A, ps-PLA1 ICC-IF

HPA036079 PRSS36, FLJ90661 IHC

HPA030522 PCNA IHC, WB, ICC-IF

HPA003210 RIBC2, C22orf11, FLJ25720 IHC

HPA021438 SH3GLB2, KIAA1848 IHC, WB, ICC-IF

HPA011935 SLC2A8, GLUT8, GLUTX1 IHC

HPA053545 TEX30, C13orf27 IHC, WB

HPA017284 TARDBP, ALS10, TDP-43 IHC, WB, ICC-IF

HPA003246 TNFRSF13C, BAFFR, CD268 IHC, WB

HPA048464 ZER1, C9orf60, Hzyg, ZYG, ZYG11BL WB, ICC-IF

左图：使用抗PON2抗体 (HPA029193) 对宫颈癌（女性，44岁）进行的免疫组织化检测，肿瘤细胞的细胞质/核染色呈棕色。右图：使用抗EAF2抗体(HPA008411) 作为对照（仅载体转染HEK293T裂解物）和 EAF2过表达裂解物（在哺乳动物 HEK293T细胞中与C端myc-DDK 标签（~3.1 kDa）共表达）进行蛋白质印迹分析， LY413036）