艾美捷人重组MEGACD40L蛋白（可溶性）特点：

1、高活性MEGACD40L®低聚物模拟体内膜辅助CD40L聚集和刺激，无需增强剂

2、高纯度，低内毒素水平

3、经验丰富的制造可实现一致可靠的批量性能

4、优化配方，提高稳定性和活性

图2：使用1000ng/mL的B细胞活化试验对连续7个生产批次的MEGACD40L®进行测试。图1：通过MEGACD40L®（ALX-522-110）激活B细胞淋巴细胞。方法：将外周血单核细胞（PBMC）在37°C、5%CO2下在48孔板（1 x 106个细胞/孔）中孵育48小时。每个孔含有200µl无血清测试培养基和连续稀释的MEGACD40L®。处理后，清洗细胞，用小鼠抗人CD19–PE和小鼠抗人CD 86–APC双重染色，并通过流式细胞术进行分析。数据以每种MEGACD40L®浓度下共染色为CD86阳性的CD19阳性B细胞的百分比表示。

艾美捷人重组MEGACD40L蛋白（可溶性）参考文献：

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