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艾美捷LKT Labs-双叶碱#B3211参数说明:
Cas No.:485-49-4
纯度:≥98%
公式:C20H17NO6
配方重量:367.35
化学名称:6R-6-甲基-5,6-二氢-7H-[8,5]二氧杂环戊二烯并[1,3-g]异喹啉-4-基]-5H-呋喃[5,6-g][3,4]苯并二氧杂环戊烯-1-酮
IUPAC名称:6R-6-甲基-5,6-二氢-7H-[8,5]二氧戊二醇[1, 3-g]异喹啉-4-基]-5H-呋喃[5,6-g][3,4]苯并二氧杂环戊烯-1-酮
同义词:d-二葫芦碱
外观:白色至类白色粉末
LKT Labs-双叶碱文献引用:
Dela Peña IJ, Lee HL, Yoon SY, et al. The ethanol extract of Cirsium japonicum increased chloride ion influx through stimulating GABA(A) receptor in human neuroblastoma cells and exhibited anxiolytic-like effects in mice. Drug Discov Ther. 2013 Feb;7(1):18-23. PMID: 23524939.
Torkaman-Boutorabi A, Soltani S, Oryan S, et al. Involvement of the dorsal hippocampal GABA-A receptors in histamine-induced facilitation of memory in the Morris water maze. Pharmacol Biochem Behav. 2013 Apr;105:142-50. PMID: 23438692.
Ionov ID, Roslavtseva LA. Coadministration of bicuculline and NMDA induces paraplegia in the rat. Brain Res. 2012 Apr 27;1451:27-33. PMID: 22445063
Ji G, Neugebauer V. Pain-related deactivation of medial prefrontal cortical neurons involves mGluR1 and GABA(A) receptors. J Neurophysiol. 2011 Nov;106(5):2642-52. PMID: 21880942.
Costa LG, Doctor SV, Murphy SD. Antinociceptive and hypothermic effects of trimethyltin. Life Sci. 1982 Sep 13;31(11):1093-102. PMID: 6890611.
Heyer EJ, Nowak LM, Macdonald RL. Membrane depolarization and prolongation of calcium-dependent action potentials of mouse neurons in cell culture by two convulsants: bicuculline and penicillin. Brain Res. 1982 Jan 28;232(1):41-56. PMID: 7055710.
LKT Laboratories(LKT Labs)注于防癌抗癌特殊化学品研究和开发域。主要包括:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成等。同时注研究用小分子的合成,纯化和分离。主要应用于癌症和神经科学等,包括蛋白激酶抑制剂、离子通道调节剂和激活剂等。艾美捷科技是LKT Labs的中国代理商,为科研工作者提供优质的产品与服务。