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(左)自发性高血压大鼠尿14,15-DHET水平升高。
(右)妊娠高血压(先兆子痫)妇女的尿14,15-DHET水平显著与健康孕妇在98%置信度下的差异(p<0.02)
艾美捷Detroit R&D生物靶标14,15-EET/DHET高血压ELISA试剂盒# DH1用于 2,14-EET/DHET 测量的 DH15 与用于测量 1,14-DHET 的 DH15 试剂盒相同。与DH2相比,DH1的区别是样品制备步骤(不是ELISA试剂盒),其中EET被化学改变为DHET。
Detroit R&D生物靶标14,15-EET/DHET高血压ELISA试剂盒相关研究:
14,15-DHET 免疫检测试剂盒
生物靶标 14,15-DHET 人尿液 ELISA 试剂盒
用于一步纯化的14,15-DHET免疫亲和柱
14,15-脱硫醚活性酶联免疫吸附试剂盒
Detroit R&D生物靶标14,15-EET/DHET高血压ELISA试剂盒部分引用文献:
1. Liu P, Zhang S, Gao J, Lin Y, Shi G, He W, Touyz RM, Yan L, Huang H. Downregulated serum 14,15-Epoxyeicosatrienoic acid is associated with abdominal aortic calcification in patients with primary aldosteronism.Hypertension 71: 592-598, 2018.
2. Li P-S, Tao W, Yang L, Shu Y. Effect of soluble epoxide hydrolase in hyperoxic acute lung injury. Inflammation Mar24. doi: 10.1007/s10753-018-0758-y, 2018.
3. Tu R., Armstrong J., Lee K., Hammock BD, Sapirstein A., Koehler RC. Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia. Sci. Rep Mar 27;8(1):5279. doi: 10.1038/s41598-018-23504-1, 2018.
4. Chang, L-H., Lin H., Huang S., Chen I., Chu K., Chih, C., Liang Y., Lee Y., Chen Y., Lee Y, Lee I. Blockade of soluble epoxide hydrolase attenuates post-ischemic neuronal hyperexcitation and confers resilience against stroke with TrkB activation. Sci. Rep. Jan 8;8(1):118. doi: 10.1038/s41598-017-18558-6, 2018.
5. Akasaka T, Sueta D, Arima Y, Tabata N, Takasio S, Izumiya Y, Yamamoto E, Tsujita K, Kojima S, Kaikita K, Kajiwara A, Morita K, Oniki K, Saruwatari J, Nakagawa K, Hokimoto S. CYP2C19 variants and epoxy eicosatrienoic acids in patients with microvascular angina. IJC Heart & Vasculature 15: 15-20 (2017).
6. Santos JM, Joiakim J, Park J-A, Kaplan D, Putt D, Taylor RN, Kim H. Can honokiol be used to ameliorate preeclampsia? Abstract #CV-20, The 16th International Eicosanoid Conference, 2016.
Detroit R&D注于心血管疾病、癌症的研究,诊断和治疗域。涉及环境健康科学、高血压、乳腺癌和列腺癌相关研究域。艾美捷科技是Detroit R&D的中国代理商,为科研工作者提供优质的产品与服务。