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血管内皮生长因子A 多克隆抗体VEGF-A Polyclonal Antibody
点击次数:87发布时间:2016/12/24 5:20:10
更新日期:2021/11/25 13:11:30
所 在 地:中国大陆
产品型号:ABP56497
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详细内容
艾美捷科技有限公司,目前提供Abbkine高质量抗体:血管内皮生长因子A 多克隆抗体,性价比非常高。Abbkine致力于为全球生命科学研究和医疗发展提供*新的产品和技术。Abbkine设计、开发、生产并销售了一系列独特的产品,包括生命科学领域研究相关的抗体、研究试剂以及细胞功能分析产品。Abbkine的产品为科学研究中的挑战提供卓有成效的解决方案,从而为全球的科学家节省时间并提高研究效率。作为Abbkine的中国区域总代理,艾美捷科技有限公司凭借丰富的专业经验,将一如既往的为中国区域客户提供Abbkine优质的产品和技术服务。
【英文名称】:VEGF-A Polyclonal Antibody
【中文名称】:血管内皮生长因子A 多克隆抗体
【产品类型】:一抗
【供应商】:Abbkine
【产品货号】:ABP56497
【背景资料】:VEGFA(vascular endothelial growth factor A) is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of VEGFA in mice resulted in abnormal embryonic blood vessel formation. VEGFA is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of VEGFA have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site.蛋白别名为:VEGFA; VEGF; Vascular endothelial growth factor A; VEGF-A; Vascular permeability factor; VPF;基因ID为:7422;蛋白质ID:P15692
【产品规格】:30u/100ul/200ul
【应用类型】:IHC-p,ELISA补充:*优的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: IHC-p: 1:100-1:300, ELISA: 1:10000. Not yet tested in other applications.
【免疫原】:合成多肽:the Internal region of human VEGF-A.
【来源宿主】:兔
【反应性】:人,小鼠,大鼠
【保存建议】:厂家推荐蓝冰运输.在发货后能在-20℃保存1年.为限度的避免损失,请在打开管盖之前融化抗体并离心.我们建议使用前分装以避免反复冻融.本产品为液体形式,溶解于PBS缓冲液中,含50%甘油,0.5%BSA和0.02%叠氮化钠.
【产品说明】:点击:血管内皮生长因子A 多克隆抗体查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-857垂询Abbkine中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看每日生物评论网站。
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