MCE 的所有产品仅用作科学研究，我们不为任何个人用途提供产品和服务。

Eriodictyol

CAS No. : 552-58-9

MCE 站：Eriodictyol

产品活性：Eriodictyol 是从中草药中得到的黄酮类，具有抗氧化、抗炎的功效。Eriodictyol 能够诱导 Nrf2 信号通路。

研究领域：Metabolic Enzyme/Protease  |  NF-κB

作用靶点：Endogenous Metabolite  |  Keap1-Nrf2

In Vitro: Eriodictyol is a flavonoid isolated from the Chinese herb, with antioxidant and anti-inflammatory activity. Eriodictyol (20, 40, 80 μM) protects primary cultured cortical neurons against Aβ_25-35-induced cytotoxicity and cell apoptosis via the Nrf2/ARE pathway. Eriodictyol (80 μM) induces nuclear expression of Nrf2 and the expression of ARE-regulated genes in primary cultured cortical neurons.

In Vivo: Eriodictyol shows protective effect against LPS-induced acute lung injury (ALI). Eriodictyol (30 mg/kg, p.o.) decreases the production of inflammatory cytokines, elevates survival rate, and decreases oxidative stress levels in LPS-induced ALI mice. Eriodictyol inhibits MPO activity and inflammatory neutrophil accumulation in the lung tissues. Eriodictyol treatment also enhances Trx1 expression by upregulating the Nrf2 expression in lung tissues.

相关产品：Human Endogenous Metabolite Compound Library  |  Traditional Chinese Medicine Monomer Library  |  Natural Product Library Plus  |  Anti-Aging Compound Library  |  Antioxidants Compound Library  |  NF-κB Signaling Compound Library  |  Oxygen Sensing Compound Library  |  Natural Product Library  |  Ferroptosis Compound Library  |  Metabolism/Protease Compound Library  |  Medicine Food Homology Compound Library  |  Bioactive Compound Library Plus  |  Immunology/Inflammation Compound Library  |  Rapamycin  |  3-Methyladenine  |  5-Fluorouracil  |  Acetylcysteine  |  ML385  |  Docetaxel  |  Hydrocortisone  |  ATP  |  Retinoic acid  |  Estradiol  |  Melatonin  |  Cytarabine  |  Prostaglandin E2  |  Isoprenaline hydrochloride  |  Curcumin  |  Calcitriol  |  Nicotinamide  |  (-)-Epigallocatechin Gallate  |  4-Octyl Itaconate  |  Bardoxolone (methyl)  |  TBHQ  |  Acetaminophen  |  Cyclopamine  |  Sulforaphane  |  Liothyronine  |  Genistein  |  (R)-(-)-Phenylephrine hydrochloride  |  DHEA  |  Digoxin  |  Corticosterone

品牌介绍:
•   MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供*新*全的高品质小分子活性化合物；
•   10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种期刊及制药收录了MCE客户的科研成果；
•   专业团队跟踪*新的制药及生命科学研究进展，为您提供全球*新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。