MCE 的所有产品仅用作科学研究，我们不为任何个人用途提供产品和服务。

Irisflorentin

CAS No. : 41743-73-1

MCE 站：Irisflorentin

产品活性：Irisflorentin 是一种天然存在的异黄酮，是 Rhizoma Belamcandae 中丰富的一种活性成分。Irisflorentin 显着降低了诱导型一氧化氮合酶 (iNOS) 的转录和翻译水平以及 NO 产生。

研究领域：Immunology/Inflammation

作用靶点：NO Synthase

In Vitro: Irisflorentin does not affect the LPS-stimulated RAW 264.7 macrophages viability up to a concentration of 40 μM.
Irisflorentin (10-40 μM) inhibits the LPS-induced production of NO in a concentration-dependent manner without affecting the iNOS activity in RAW 264.7 macrophages.
Irisflorentin (10-40 μM) concentration dependently inhibits the LPS (10 ng/mL)-induced increase in iNOS mRNA expression in LPS stimulated RAW 264.7 macrophages. Irisflorentin (10-40 μM) concentration-dependently suppresses the production of TNF-α, IL-1β and IL-6 in LPS stimulated RAW 264.7 macrophages.
Irisflorentin (10-40 μM) concentration dependently inhibits the LPS (10 ng/mL)-induced increase in iNOS protein levels. Irisflorentin (10-40 μM) concentration-dependently suppresses LPS-induced p38 and ERK1/2 phosphorylation in a concentration-dependent manner, but slightly affects JNK phosphorylation.

相关产品：Traditional Chinese Medicine Monomer Library  |  Natural Product Library Plus  |  Anti-Aging Compound Library  |  Natural Product Library  |  Medicine Food Homology Compound Library  |  Bioactive Compound Library Plus  |  Immunology/Inflammation Compound Library  |  FDA Approved & Pharmacopeial Drug Library  |  L-NAME hydrochloride  |  L-NMMA acetate  |  1400W Dihydrochloride  |  Asymmetric dimethylarginine  |  20-HETE  |  Methylene Blue  |  GW274150  |  L-Arginine  |  Tat-NR2B9c  |  Chondroitin sulfate  |  Tetrahydrobiopterin  |  Ginsenoside C-K  |  Agmatine sulfate  |  AVE-3085  |  L-NIO dihydrochloride  |  Prim-O-glucosylcimifugin  |  6-Biopterin  |  Isoquercetin  |  L-Canavanine sulfate  |  L-NIL  |  S-Nitroso-N-acetyl-DL-penicillamine  |  Isosorbide dinitrate  |  Kuwanon A  |  Luteolin 5-O-glucoside  |  3-Bromo-7-nitroindazole  |  Ciwujianoside C3  |  Ginsenoside Rb3

品牌介绍:
•   MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供*新*全的高品质小分子活性化合物；
•   10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种期刊及制药收录了MCE客户的科研成果；
•   专业团队跟踪*新的制药及生命科学研究进展，为您提供全球*新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。