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Human growth hormone-releasing factor TFA

CAS No. :

MCE 站：Human growth hormone-releasing factor TFA

产品活性：Human growth hormone-releasing factor TFA (Growth Hormone Releasing Factor human TFA) 是一种下丘脑多肽，通过与脑垂体前细胞生长激素释放激素受体 (GHRHR) 结合，从而刺激生长激素的生成和释放。

研究领域：GPCR/G Protein

作用靶点：GHSR

In Vitro: The GHRHR is a member of the class II B GPCR family, which couples predominantly to the Gs-adenylate cyclase-cAMP signaling pathway. Peptide hormones that activate class II GPCRs include GHRH, secretin, glucagon-like peptides, gastric-inhibitory peptide (GIP), pituitary adenylate cyclase-activating peptide, corticotropin-releasing hormone, vasoactive intestinal peptide, parathyroid hormone, ａnd calcitonin-related peptides.
GHRH, expressed in the arcuate nucleus of the hypothalamus ａnd released into portal vasculature, directly stimulates growth hormone synthesis ａnd secretion from the pituitary somatotropes by activating the corresponding GHRH receptors.

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