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FD-1080

CAS No. : 1151666-58-8

MCE 站：FD-1080

产品活性：FD-1080 是在 NIR-II 区域中具有激发和发射光的荧光团 (Ex=1064 nm, Em=1080 nm)，可用于体内成像。

研究领域：Others

作用靶点：Others

In Vitro: FD-1080 shows superior photostability under the continuous laser irradiation. The quantum yield of FD-1080 is 0.31%, ａnd can be increased to 5.94% after combining with fetal bovine serum (FBS) to form FD-1080-FBS complexes.

In Vivo: The 1064 nm NIR-II excitation of FD-1080 is demonstrated with the high tissue penetration depth ａnd superior imaging resolution compared to NIR excitation from 650 nm to 980 nm. Deeptissue ａnd high-resolution in vivo imaging for the left hindlimb vasculature, abdomen, ａnd brain vessels was realized, allowing penetration through intact skin, tissue, ａnd skull. FD-1080 also quantifying the respiratory rate based on the dynamic imaging of respiratory craniocaudal motion of the liver for the awake ａnd anaesthetized mouse.

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