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Deoxycytidine triphosphate trisodium salt
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Deoxycytidine triphosphate trisodium salt
CAS No. : 109909-44-6
MCE 站:Deoxycytidine triphosphate trisodium salt
产品活性:Deoxycytidine triphosphate trisodium salt (dCTP trisodium salt) 是可用于 DNA 合成 (DNA synthesis) 的核苷三磷酸。Deoxycytidine triphosphate trisodium salt 可用于实时 PCR,cDNA 合成 和 DNA 测序等研究。
研究领域:Cell Cycle/DNA Damage | Metabolic Enzyme/Protease
作用靶点:DNA/RNA Synthesis | Nucleoside Antimetabolite/Analog | Endogenous Metabolite
In Vitro: Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to growth inhibition by 1-β-D-arabinofuranosylcytosine (ara-C) revealed a spectrum between the most and least sensitive which differed 100-fold from each other. An inverse correlation between sensitivity and cellular Deoxycytidine triphosphate (2′-Deoxycytidine-5′-triphosphate, dCTP) content is found, and this suggested that sensitivity of cells might be increased if the dCTP content was lowered during cell exposure to ara-C.
Deoxycytidine triphosphate trisodium salt is a phosphoethanolamine cytidylyltransferase substrate.
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