MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Anti-Alzheimer’s Disease Compound Library

MCE 站：Anti-Alzheimer’s Disease Compound Library

Alzheimer’s Disease (AD) is a progressive degenerative brain disease which causes mental and physical decline, gradually resulting in death. Despite the significant public health issue that it poses, only few medical treatments have been approved for Alzheimer’s Disease (AD) and these act to control symptoms rather than alter the course of the disease. Discovery of new therapeutic approaches depends on the study of pathology of AD. Recent research findings have led to greater understanding of disease neurobiology in Alzheimer's Disease (AD) and identification of unique targets for drug development. Several important mechanisms have been proposed to explain the underlying pathology of AD, such as Amyloid cascade hypothesis, Tau hypothesis and Cholinergic hypothesis, etc. MCE offers a unique collection of 622 compounds with anti-Alzheimer’s Disease activities or targeting the unique targets of AD. MCE Anti-Alzheimer’s Disease Compound Library is a useful tool for exploring the mechanism of AD and discovering new drugs for AD.

Description & Advantages:

?   A unique collection of 622 compounds for high throughput screening (HTS) and high content screening (HCS).

?   Targets include Amyloid-β, 5-HT Receptor, 5-HT Receptor, nAChR,etc.

?   A useful tool for exploring the mechanism of Alzheimer's disease and looking for new treatments.

?   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

?   Structurally diverse, medicinally active, and cell permeable.

?   Detailed compound information with structure, IC₅₀, and brief introduction.

?   Validated NMR and HPLC to ensure high purity and quality.

?   All compounds are in stock and continuously updated.

品牌介绍:
•   MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供*新*全的高品质小分子活性化合物；
•   10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种期刊及制药收录了MCE客户的科研成果；
•   专业团队跟踪*新的制药及生命科学研究进展，为您提供全球*新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。