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GPCR/G Protein Compound Library

MCE 站：GPCR/G Protein Compound Library

GPCRs are a large family of cell surface receptors that respond to a variety of external signals. Binding of a signaling molecule to a GPCR results in G protein activation, which in turn triggers the production of any number of second messengers. GPCRs play an important role in the human body, and increased understanding of these receptors has greatly affected modern medicine. In fact, researchers estimate that between one-third to one-half of all approved drugs act by binding to GPCRs. GPCRs are a large group of drug targets in drug discovery.MCE provide a unique collection of 1431 small molecules targeting GPCRs that can be used in the screening for various GPCRs-related research and drug development projects.

Description & Advantages:

?   A unique collection of 1431 small molecules targeting G protein coupled receptors used in GPCR screening for various research and drug development projects.

?   Targets such as 5-HT Receptor, Dopamine Receptor, Opioid Receptor, Adrenergic Receptors, Cannabinoid Receptor, mGluR, ETA Receptor, etc.

?   The most successful class of drugable targets in the human genome and remain the most attractive family of targets.

?   All of the small molecules in the GPCR library are well characterized with biological and pharmaceutical activity. Some compounds have been approved by the FDA.

?   A powerful tool for discovering GPCR-based drugs that are the richest signal receptor targets for drug discovery.

?   Structurally diverse, medicinally active, and cell permeable.

?   Rich documentation with structure, IC₅₀, and brief introduction.

?   NMR and HPLC validated to ensure the highest purity.

?   All compounds are in stock and continuously updated.

品牌介绍:
•   MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供*新*全的高品质小分子活性化合物；
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•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
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