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Oxindole
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Oxindole
CAS No. : 59-48-3
MCE 站:Oxindole
产品活性:Oxindole (Indolin-2-one) 是芳族杂环砌块。 Oxindole衍生物已成为激酶抑制剂研究中的主要化合物。
研究领域:Anti-infection
作用靶点:HIV
In Vitro: Oxindole (Indolin-2-one) is a bicyclic structure consisting of a benzene ring fused to 2-pyrrolidone. Substituted indolis can be referred as ‘privileged structures’ owing to their excellent binding affinity for many receptors and to the number of approved drugs containing this scaffold. Oxindole has been found in tissues and fluids of mammals as well as natural products produced by a range of plants, bacteria and invertebrates. 2-indoli derivatives possess diverse range of pharmacological activities including anti-cancer, anti-HIV, anti-diabetic, antibacterial, antioxidant, kinase inhibitory, AChE inhibitory, anti-leishmanial, b3 adrenergic receptor agonistic, phosphatase inhibitory, analgesic, spermicidal, vasopressin antagonists, progesterone antagonists, neuroprotection, NMDA blocker and sleep inducing activities.
相关产品:Natural Product Library Plus | Bioactive Compound Library Plus | Anti-Infection Compound Library | Immunology/Inflammation Compound Library | Kinase Inhibitor Library | Natural Product Library | Anti-Cancer Compound Library | Antiviral Compound Library | Fragment Library | Diabetes Related Compound Library | Endocrinology Compound Library | Neuroprotective Compound Library | Alkaloids Library | Doxorubicin hydrochloride | Chloroquine | 5-Fluorouracil | Valproic acid | (-)-Epigallocatechin Gallate | Shikonin | Ivermectin | Ebselen | Kaempferol | Flavopiridol | Maraviroc | Hydroxyurea | Dimethyl fumarate | Baicalin | Probenecid | Ritonavir | Fasudil Hydrochloride | Lopinavir | Betulinic acid | Lamivudine | Rolipram | Nelfinavir Mesylate | Oltipraz | Saquinavir | Rottlerin | Cepharanthine | Zidovudine
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热门标签:Indolin-2-one