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Isoquercetin

CAS No. : 482-35-9

MCE 站：Isoquercetin

产品活性：Isoquercetin (Quercetin 3-glucoside) 是天然存在的多酚，具有抗氧化，抗增殖和抗炎特性。Isoquercetin 通过 Nrf2/ARE 抗氧化剂信号传导途径减轻乙醇诱导的肝毒性，氧化应激和炎症反应。Isoquercetin 通过调节核因子-κB (NF-κB) 转录调节系统调节一氧化氮合酶 2 (NO2) 的表达。Isoquercetin 具有高生物利用度和低毒性，是预防糖尿病妊娠出生缺陷的有希望的候选药物。

研究领域：NF-κB  |  Immunology/Inflammation

作用靶点：NF-κB  |  NO Synthase

In Vitro: Isoquercetin (Quercetin 3-glucoside; 5-20 μM; 24 hours) substantially reduces ethanol-induced cytotoxicity , protects hepatic cells against ethanol-stimulated liver injury.Isoquercetin (10 μM; pre-treat 1 hour) dramatically downregulates the levels of ethanol-induced iNOS protein expression in HepG2 cells.

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