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Isoimperatorin
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Isoimperatorin
CAS No. : 482-45-1
MCE 站:Isoimperatorin
产品活性:Isoimperatorin 是Angelica dahurica 根的甲醇提取物,有效抑制乙酰胆碱酯酶 (AChE),IC50 为 74.6 μM。
研究领域:Neuronal Signaling | Anti-infection
In Vitro: During a screening program for new agrochemicals from Chinese medicinal herbs, the ethanol extract of Notopterygium incisum rhizomes is found to possess strong nematicidal activity against the two species of nematodes, Bursaphelenchus xylophilus and Meloidogyne incognita. Based on bioactivity-guided fractionation, the four constituents are isolated from the ethanol extract and identified as Columbianetin, Falcarindiol, Falcarinol, and Isoimperatorin. Isoimperatorin also has LC50 values of 21.83 μg/mL against B. xylophilus. When using 15 min UV light treatment, falcarindiol, falcarinol, and isoimperatorin demonstrated almost five times more toxic to the southern root-knot nematodes than in dark treatment while columbianetin showed only two times more toxic. isoimperatorin has been demonstrated to possess insecticidal activity against several insects, such as the cabbage aphid (Brevicoryne brassicae). Isoimperatorin is identified in the active fraction of Angelica dahurica (AD) extract. Isoimperatorin is usually used as the internal standard (IS).
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