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3-Amino-2-methylpropanoic acid
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3-Amino-2-methylpropanoic acid
CAS No. : 144-90-1
MCE 站:3-Amino-2-methylpropanoic acid
产品活性:3-Amino-2-methylpropanoic acid 会诱导白色脂肪发生褐变,并与心血管代谢危险因素成反比。
研究领域:Metabolic Enzyme/Protease
In Vivo: Weight is slightly decreased in the mice by the end of 3-Amino-2-methylpropanoic acid (BAIBA) treatment. Analysis of body composition using MRI demonstrates BAIBA treatment significantly decreases body fat in the mice. Consistent with the effects on thermogenic and β-oxidation gene expression and body weights, analysis with metabolic cages indicates that oxygen consumption (VO2) and whole body energy expenditure are increased in the BAIBA treated mice without any significant difference in activity or food intake. The mice are also challenged with an intraperitoneal glucose tolerance test (IPGTT). BAIBA is found to significantly improve the glucose tolerance in the mice as determined by the area under the curve of the IPGTT.
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热门标签:3amino2methylpropanoic 3