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Molecular Chaperones Library

MCE 站：Molecular Chaperones Library

Molecular Chaperones Library comprises 2,468 synthetic compounds targeting most promising and studied targets: Heat shock proteins (Hsp90, Hsp82, Hsp27), chaperone activity of bc1 complex-like and histone-chaperone ASF1a complex (ASF1-histone interaction).

Description & Advantages:

?   A set of 2,468 compounds targeting molecular chaperones; designed by ligand-based methods.

?   No PAINS (Pan Assay Interference Compounds), only medchem friendly compounds.

?   Full Rule of Five compliance.

?   Structurally diverse.

?   NMR and HPLC validated to ensure high purity and quality.

?   All compounds can be readily followed with analogues either from stock or from new syntheses.

?   Databases and compounds are provided by Enamine.

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