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λ-Cyhalothrin
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λ-Cyhalothrin
CAS No. : 91465-08-6
MCE 站:λ-Cyhalothrin
产品活性:λ-Cyhalothrin 是一种高效的广谱的 II 型合成除虫菊酯杀虫剂,含有 α-氰基。λ-Cyhalothrin 在各种应用中用于防治多种害虫 (pests)。λ-Cyhalothrin 是一种神经毒素,靶向中枢神经系统中神经元膜的钠通道 (sodium channels)。
研究领域:Anti-infection | Membrane Transporter/Ion Channel
作用靶点:Parasite | Sodium Channel
In Vitro: The mechanism of λ-Cyhalothrin toxicity produces delay in sodium channel inactivation, which leads to persistent depolarization of the nerve membrane. λ-Cyhalothrin produces membrane depolarization, calcium ion infl ux, and neurotransmitter release from rat brain synaptosomes.
λ-Cyhalothrin possesses estrogenic properties and has an ability to function as a xenoestrogen promoting human breast carcinoma cell proliferation in vitro.
λ-Cyhalothrin has found multiple uses in pest (fleas, cockroaches, flies, and ants) control.
λ-Cyhalothrin is highly effective against the malaria transmitting species of Anopheles.
In Vivo: The effect of λ-Cyhalothrin (i.p.) on memory, movement activity, and co-ordination in mice exposed to bilateral clamping of the carotid arteries (BCCA) is investigated. Neither memory nor movement co-ordination are impaired by BCCA or λ-Cyhalothrin. Exploratory locomotor activity is significantly reduced in the BCCA/LCH group. Spontaneous movement activity is significantly reduced in the BCCA/λ-Cyhalothrin group . Exposure to λ-Cyhalothrin coexisting with BCCA decreases motor activity in the mice in 2 subsequent 30-min.
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