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Posenacaftor sodium

CAS No. : 2095064-06-3

MCE 站：Posenacaftor sodium

产品活性：Posenacaftor (PTI-801) sodium 是一种囊性纤维化跨膜调节蛋白 (CFTR) 调节剂，可纠正 CFTR 蛋白的折叠和运输。Posenacaftor sodium 用于囊性纤维化 (CF) 的研究。

研究领域：Membrane Transporter/Ion Channel

作用靶点：CFTR

In Vitro: Cystic fibrosis (CF) is an autosomal recessive disorder, caused by mutations of the cystic fibrosis transmembrane conductance regulator (CFTR).
CFTR is a cAMP-regulated chloride channel that is primarily located at the apical membrane of epithelial cells.Mutations in the?CFTR?gene lead to the production of a defective and misfolded CFTR protein, and impairs the flow of ions in and out of cells.
Posenacaftor is a?CFTR corrector, correctors are always designed to fix and restore the function of the defective CFTR protein. The corrected CFTR then moves to the cell surface, where it functions as a chloride channel and helps maintain the right balance of fluid in the airways.

相关产品：Drug Repurposing Compound Library Plus  |  Clinical Compound Library Plus  |  Bioactive Compound Library Plus  |  Immunology/Inflammation Compound Library  |  Membrane Transporter/Ion Channel Compound Library  |  Clinical Compound Library  |  Drug Repurposing Compound Library  |  K41498 TFA  |  Kobusin  |  PG01

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