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Esmolol hydrochloride

CAS No. : 81161-17-3

MCE 站：Esmolol hydrochloride

产品活性：Esmolol hydrochloride 是一种 β 肾上腺素受体抑制剂。

研究领域：GPCR/G Protein  |  Neuronal Signaling  |  Autophagy

作用靶点：Adrenergic Receptor  |  Autophagy  |  Mitophagy

In Vitro: Esmolol hydrochloride is the hydrochloride salt form of Esmolol, a short and rapid-acting beta adrenergic antagonist belonging to the class II anti-arrhythmic drugs and devoid of intrinsic sympathomimetic activity. Esmolol hydrochloride competitively blocks beta-1 adrenergic receptors in cardiac muscle and reduces the contractility and cardiac rate of heart muscle, thereby decreasing cardiac output and myocardial oxygen demands. This agent also decreases sympathetic output centrally and blocks renin secretion. At higher doses, Esmolol hydrochloride also blocks beta-2 receptors located in bronchial and vascular smooth muscle, thereby leading to smooth muscle relaxation.

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