MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

L-4-Oxalysine hydrochloride

CAS No. : 118021-35-5

MCE 站：L-4-Oxalysine hydrochloride

产品活性：L-4-Oxalysine hydrochloride是从中国的链霉菌培养基中分离的天然物质，具有抗癌活性。

研究领域：Anti-infection

作用靶点：Fungal

In Vitro: Alpha-fetoprotein (AFP) is expressed in BEL-7404 human hepatoma cells and L-4-Oxalysine suppresses AFP mRNA expression in the cells. L-4-oxalysine functionally antagonizes the a-fetoprotein-induced suppression of the mitogen- and one-way mixed lymphocyte culture-induced proliferation of spleen lymphocytes and interleukin-6 production by these cells in mice bearing the hepatoma-22 tumor.

In Vivo: Tbe ultrastructural efects of different doses of L-4-Oxalysine on hepatocytes in mice are most serious at day 1 after stopping treatment. Mice are given ig L-4-oxalysine (I-677) 10, 50, and 100 mg/kg for 7 d. On day 8 the hepatocytes show accumulation of lipid droplets followed by loss of matrices in cytoplasm. The total area of lipid droplets is far less than 25% of mean section of hepatocytes. The injury of mitochondria and RER is only found in the groups of medium and high dose. L-4-oxalysine inhibits the proliferation of some mouse implanted tumors and pulmonary metastasis of mouse Lewis lung carcinoma.

相关产品：Rapamycin  |  Ferrostatin-1  |  Cycloheximide  |  Staurosporine  |  Resveratrol  |  Tunicamycin  |  Hygromycin B  |  Oligomycin A  |  Camptothecin  |  Amphotericin B  |  Nystatin  |  Calcimycin  |  Filipin complex  |  Mycophenolic acid  |  Idarubicin hydrochloride  |  Fluconazole  |  Ketoconazole  |  Itraconazole  |  Caspofungin Acetate  |  Oligomycin  |  Posaconazole  |  Toyocamycin  |  Voriconazole  |  Cerulenin  |  Ciclopirox olamine  |  Isavuconazole  |  Leptomycin B  |  Hyperoside  |  Terbinafine  |  Anidulafungin

品牌介绍:
•   MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供*新*全的高品质小分子活性化合物；
•   10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种期刊及制药收录了MCE客户的科研成果；
•   专业团队跟踪*新的制药及生命科学研究进展，为您提供全球*新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。