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BPC 157

CAS No. : 137525-51-0

MCE 站：BPC 157

产品活性：BPC 157 是一种稳定的胃十五肽，是人胃液蛋白 BPC 的部分序列。BPC 157 是一种抗溃疡肽能剂，没有报道毒性。BPC 157 与炎症性肠病和多发性硬化症有关。

研究领域：Metabolic Enzyme/Protease

作用靶点：Endogenous Metabolite

In Vivo: BPC 157 successfully heals the intestinal anastomosis, gastrocutaneous, duodenocutaneous ａnd colocutaneous fistulas in rats, as well as interacting with the NO-system.
BPC 157 (10 μg/kg, 10 ng/kg) is applied either intraperitoneally once time daily (first application immediately after surgery, last at 24 hours before sacrifice) or per-orally in drinking water (0.16 μg/ml/12 ml/day till the sacrifice). A multiple sclerosis suited toxic rat model, cuprizone (compared with standard, a several times higher regimen, 2.5% of diet regimen + 1 g/kg intragastrically/day) was combined with BPC 157 (in drinking water 0.16 μg or 0.16 ng/ml/12 ml/day/rat + 10 μg or 10 ng/kg intragastrically/day) till the sacrifice at day 4. In general, the controls could not heal cysteamine colitis ａnd colon-colon anastomosis. BPC 157 induced an efficient healing of both at the same time.

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