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Monazomycin

CAS No. : 11006-31-8

MCE 站：Monazomycin

产品活性：Monazomycin 是由链霉菌产生的多烯类抗生素。Monazomycin 的分子量约为 1200。

研究领域：Anti-infection

作用靶点：Antibiotic

In Vitro: Monazomycin is an antibiotic produced by Streptomyces. Its molecular weight is about 1200, ａnd is related to that of polyene antibiotics. Monazomycin has an amino group that gives a positive charge to the molecule at neutral pH. When monazomycin is added in micromolar amounts to one side of a bilayer, membrane conductance becomes strongly voltage-dependent. Monazomycin is present in the solution in the form of relatively hydrophilic clusters ａnd is adsorbed as such on top of the lipid bilayer, penetration into the bilayer following a potential jump is assumed to be preceded by a potential-independent disaggregation of the adsorbed clusters into adsorbed monomers.

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