MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Mivacurium dichloride

CAS No. : 106861-44-3

MCE 站：Mivacurium dichloride

产品活性：Mivacurium dichloride 是一种苄基异喹啉衍生物，也是一种短效非去极化神经肌肉阻滞剂和骨骼肌松弛剂。Mivacurium dichloride 可与 nAChR 偶联，以减少或抑制乙酰胆碱对肌肉细胞末端盘的去极化作用。

研究领域：Membrane Transporter/Ion Channel  |  Neuronal Signaling

作用靶点：nAChR

In Vitro: Mivacurium induces LAD2 cell degranulation in a dose-dependent manner. Mivacurium stimulates intracellular Ca²⁺ influx in MRGPRX2-HEK293 cells but not in NC-HEK293 cells. Mivacurium induces the release of only low levels of mediators in LAD2 cells transfected with MRGPRX2-targeted small interfering siRNA.

In Vivo: Mivacurium causes pseudo-allergic reactions in C57 wild-type mice by inducing mast cells to release histamine and a decrease in body temperature.
Mivacurium is rapidly hydrolyzed in the plasma and has a short duration of action (< 10 min). Mivacurium has many advantages, such as a rapid effect, nonneurological toxicity and a lack of heart rate alteration.

相关产品：Drug Repurposing Compound Library Plus  |  FDA-Approved Drug Library Plus  |  Bioactive Compound Library Plus  |  Membrane Transporter/Ion Channel Compound Library  |  Neuronal Signaling Compound Library  |  FDA-Approved Drug Library  |  Drug Repurposing Compound Library  |  NMPA-Approved Drug Library  |  Neurotransmitter Receptor Compound Library  |  FDA Approved & Pharmacopeial Drug Library  |  Drug-Induced Liver Injury (DILI) Compound Library  |  Anti-Parkinson's Disease Compound Library  |  Neurodegenerative Disease-related Compound Library  |  Methyllycaconitine citrate  |  Acetylcholine chloride  |  PNU-282987  |  GTS-21 dihydrochloride  |  Carbamoylcholine chloride  |  Arecoline hydrobromide  |  Benzethonium chloride  |  D-Tubocurarine chloride pentahydrate  |  Encenicline hydrochloride  |  PNU-120596  |  Varenicline Hydrochloride  |  Cisatracurium besylate  |  Mecamylamine hydrochloride  |  Atracurium besylate  |  Varenicline Tartrate  |  Anabasine  |  Hexamethonium Bromide  |  Lobeline hydrochloride  |  ABT-418 hydrochloride  |  Hydroxybupropion  |  NS 1738  |  BNC210  |  Galanthamine hydrobromide  |  SSR180711 hydrochloride  |  Adiphenine hydrochloride  |  Meclofenoxate hydrochloride  |  Monepantel  |  Sofiniclin  |  Cytisinicline

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  染料试剂  |  PROTAC  |  同位素标记物

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Dye Reagents  |  PROTAC  |  Isotope-Labeled Compounds

品牌介绍:
•   MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供*新*全的高品质小分子活性化合物；
•   10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种期刊及制药收录了MCE客户的科研成果；
•   专业团队跟踪*新的制药及生命科学研究进展，为您提供全球*新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。