MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Levalbuterol hydrochloride

CAS No. : 50293-90-8

MCE 站：Levalbuterol hydrochloride

产品活性：Levalbuterol ((R)-Albuterol) hydrochloride 是短效 β2-肾上腺素受体 (β2-adrenergic receptor) 激动剂和 Salbutamol 的活性 R 型对映异构体。Levalbuterol hydrochloride 是一种比 Salbutamol 更有效的支气管扩张试剂，可用于哮喘和慢性阻塞性肺疾病 (COPD) 的研究。

研究领域：GPCR/G Protein  |  Neuronal Signaling

作用靶点：Adrenergic Receptor

In Vitro: Levalbuterol (10 μM; 24 hours) hydrochloride induces 11β-HSD1 mRNA expression, however, it does not influence 11β-HSD2expression in airway epithelial cells.
Levalbuterol (10 μM; 24 hours) hydrochloride significantly reduces both LPS- ａnd TNF-α-induced NF-κB activity while increasing GRE activation in an 11β-HSD1 dependent manner in a transformed mouse airway epithelial cell line.

In Vivo: Levalbuterol (subcutaneous injection; 1 mg/kg; 14 days) hydrochloride significantly decreases pulmonary inflammation in OVA mice, demonstrated a decrease in eosinophilia ａnd IgE.

相关产品：Drug Repurposing Compound Library Plus  |  FDA-Approved Drug Library Plus  |  FDA-Approved Drug Library Mini  |  Bioactive Compound Library Plus  |  GPCR/G Protein Compound Library  |  Immunology/Inflammation Compound Library  |  Neuronal Signaling Compound Library  |  FDA-Approved Drug Library  |  Drug Repurposing Compound Library  |  Orally Active Compound Library  |  Neurotransmitter Receptor Compound Library  |  FDA Approved & Pharmacopeial Drug Library  |  Anti-Obesity Compound Library  |  Antidepressant Compound Library  |  Protein-protein Interaction Inhibitor Library  |  Isoprenaline hydrochloride  |  Norepinephrine  |  ICI 118,551 hydrochloride  |  Propranolol hydrochloride  |  Phenylephrine  |  CL 316243  |  Pimozide  |  Carvedilol  |  Prazosin hydrochloride  |  Atenolol  |  Yohimbine Hydrochloride  |  Dexmedetomidine hydrochloride  |  Mirabegron  |  Amitriptyline hydrochloride  |  YS-49  |  Metoprolol Succinate  |  2＇,5＇-Dideoxyadenosine  |  Nebivolol hydrochloride  |  Phentolamine mesylate  |  Dobutamine hydrochloride  |  Labetalol hydrochloride  |  (S)-Timolol Maleate  |  Bisoprolol hemifumarate  |  Pindolol

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  染料试剂  |  PROTAC  |  同位素标记物  |  寡核苷酸

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Dye Reagents  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides

品牌介绍:
•   MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供*新*全的高品质小分子活性化合物；
•   10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种期刊及制药收录了MCE客户的科研成果；
•   专业团队跟踪*新的制药及生命科学研究进展，为您提供全球*新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。