MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Oxytetracycline calcium

CAS No. : 7179-50-2

MCE 站：Oxytetracycline calcium

产品活性：Oxytetracycline calcium 是一种属于四环素类的抗生素。Oxytetracycline calcium强力抑制革兰氏阴性和革兰氏阳性细菌。Oxytetracycline calcium 是一种蛋白质合成抑制剂，可阻止 aminoacil-tRNA 与复杂的核糖体 RNA 结合。Oxytetracycline calcium 还具有抗 HSV-1 的活性。

研究领域：Anti-infection  |  Metabolic Enzyme/Protease

作用靶点：Bacterial  |  HSV  |  Antibiotic  |  Endogenous Metabolite

In Vitro: Oxytetracycline calcium is an important member of the bacterial aromatic polyketide family, which is a structurally diverse class of natural products. Oxytetracycline calcium is synthesized by a type II polyketide synthase that generates the poly-beta-ketone backbone through successive decarboxylative condensation of malonyl-CoA extender units, followed by modifications by cyclases, oxygenases, transferases, ａnd additional tailoring enzymes.

In Vivo: The effects of administration a therapeutic dose of Oxytetracycline (82.8 mg/kg of bw to 1 % bw/day) calcium for 10 days are species specific. Oxytetracycline calcium increases the relative liver weight in Morone chrysops x M. saxatilis, the enzymatic activity of CYP3A4 in Ictalurus punctatus, protein expression of CYP3A4 in Oreochromis niloticus ａnd depleted the hepatic CYP3A4 in the latter.
For Oxytetracycline calcium, the limits are 100 μg/kg in muscle ａnd milk, 200 μg/kg in egg, 300 μg/kg in liver ａnd 600 μg/kg in kidney. Oxytetracycline calcium is administered to fish as medicated feed at concentrations ranging from 35 to 75 mg a.i kg-1 biomass day-1 for 7-14 days.

相关产品：Rapamycin  |  3-Methyladenine  |  Chloroquine  |  Doxorubicin hydrochloride  |  Bafilomycin A1  |  Puromycin dihydrochloride  |  Acetylcysteine  |  Dexamethasone  |  Cycloheximide  |  Staurosporine  |  2-Deoxy-D-glucose  |  5-Fluorouracil  |  G-418 disulfate  |  ATP  |  Retinoic acid  |  Cyclosporin A  |  5-Azacytidine  |  Doxycycline (hyclate)  |  Etoposide  |  Nigericin sodium salt  |  CCCP  |  Hydrocortisone  |  AICAR  |  Brefeldin A  |  Actinomycin D  |  Resveratrol  |  Estradiol  |  Nicotinamide  |  Docetaxel  |  Hygromycin B

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  染料试剂  |  PROTAC  |  同位素标记物  |  寡核苷酸

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Dye Reagents  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides

品牌介绍:
•   MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供*新*全的高品质小分子活性化合物；
•   10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；
•   设有专业的实验中心和严格的质控、验证体系；
•   提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
•   产品的生物活性多经各国客户实验验证；
•   Nature, Cell, Science 等多种期刊及制药收录了MCE客户的科研成果；
•   专业团队跟踪*新的制药及生命科学研究进展，为您提供全球*新的活性化合物；
•   与世界各大制药公司及知名科研机构建立了长期的合作。