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Animal-Free BMP-15 Protein, Human (His)

MCE 站：Animal-Free BMP-15 Protein, Human (His)

Bone morphogenetic protein 15 (BMP-15; GDF9B), also known as growth differentiation factor 9B (GDF9B), is a polymorphic ligand protein of the TGFβ family ａnd is only expressed in follicular cells. BMP15 is closely related to GDF9 ａnd synergistically regulates the genetic development of follicles. BMP15 is involved in p38 MAPK ａnd HIF-1α/SCF signaling pathway, respectively, ａnd can up-regulate the expression of anti-Mullerian hormone (AMH) ａnd polycystic ovarian syndrome (PCOS) related stem cell factor (SCF) in granulosa cells. The total length of human BMP-15 protein is 392 amino acids (M1-R392), with 4 glycosylation domains. Animal-Free BMP-15 Protein, Human (His) has a total length of 125 amino acids (Q268-R392), is expressed in E. coli cells with a C-terminal His-tag.

Synonyms: Growth/Differentiation Factor-9B; GDF-9B; ODG2; POF4

Species: Human

Source: E. coli

Biological Activity: The ED₅₀ is <17 ng/mL as measure by its ability to induce alkaline phosphatase production by ATDC5 cells.

产品分类：细胞因子和生长因子  |  转化生长因子-β 超家族  |  骨形态发生蛋白  |  骨形态发生蛋白 15  |  无动物成分重组蛋白  |  重组蛋白定制服务

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