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Adipokinetic hormone I (Locusta migratoria)

CAS No. : 61627-67-6

MCE 站：Adipokinetic hormone I (Locusta migratoria)

产品活性：Adipokinetic hormone I (Locusta migratoria) (Lom-AKH-I) 是一种昆虫脂肪运动激素 (AKH)，能够提高脂肪体 cAMP 水平。AKHs 控制飞蝗从脂肪体储存库中直接动员碳水化合物和脂质，这依赖于 AKHs 受体通过刺激性鸟嘌呤核苷酸结合蛋白 (Gs) 来偶联 cAMP 形成和糖原磷酸化酶激活过程。

研究领域：Metabolic Enzyme/Protease

作用靶点：Endogenous Metabolite

In Vitro: Adipokinetic hormone I (Locusta migratoria) (radiolabeled; 1 pmol in 10 μL of 10% methanol; 30 min on ice, ａnd repeated for 2 h at 30 ℃) shows no association with one of the larger protein components, indicating a lack of separate transporting or carrier protein in the hemolymph.
Adipokinetic hormones (AKHs) are known to be involved in insect immunity ａnd shows the mechanism of metabolic stimulation, leading a significant increase in carbon dioxide production, ａnd efficacy increase of toxins produced by I. fumosorosea in the cockroach＇s body.
Adipokinetic hormone II is more effective than hormone I in bringing about an accumulation of cAMP in the fat body.

In Vivo: Adipokinetic hormone I (Locusta migratoria) (1 pmol in 10 μL of 10% methanol; injection) plays its own biol. role in the overall syndrome of insect flight, with different half-lives of 51 min ａnd 35 min during rest ａnd flight, respectively.

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