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Lysozyme chloride
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Lysozyme chloride
CAS No. : 9066-59-5
MCE 站:Lysozyme chloride
产品活性:Lysozyme chloride 是一种杀菌酶,它能裂解革兰氏阳性细菌 (bacteria)。Lysozyme chloride 还可用于 HIV 感染和肺气肿的研究。
研究领域:Anti-infection
In Vitro: Lysozyme is an ubiquitous enzyme. The hen egg is the most abundant source of Lysozyme, which constitutes approximately 3.4% of the albumen proteins. Lysozyme is a natural antimicrobial that hydrolyzes the β(1-4) glycosidic linkage between N-acetylmuramic acid and N-acetylglucosamine found in the peptidoglycan layer of the bacterial cell wall and causing cell lysis. The bactericidal effect of Lysozyme chloride is primarily limited to gram-positive bacteria, including pathogens such as Listeria monocytogenes and certain Clostridium species as well as some spoilage organisms, including thermophilic spore-forming bacteria and certain yeasts. The gram-negative bacteria are more resistant to Lysozyme chloride action because of their complex cell wall structure.
Lysozyme (1 mg/mL) chloride impairs the ability of hyaluronan (HA) to prevent elastase injury to elastic fibers.
In Vivo: Syrian hamsters exposes to aerosolized Lysozyme (20 mg in 20 ml of water; 50 min) chloride prior to elastase administration showes significantly increased airspace enlargement.
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