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Anti-Drug-Resistant Compound Library
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Anti-Drug-Resistant Compound Library
MCE 站:Anti-Drug-Resistant Compound Library
Resistance refers to the decrease in the effectiveness of drugs in treating diseases or symptoms. Due to the increasing global antibiotic resistance, it may threaten our ability to treat common infectious diseases. Drug resistance is also the main cause of chemotherapy failure in malignant tumors. In approximately 50% of cases, drug resistance exists even before chemotherapy begins. There are many mechanisms of anticancer drug resistance, including increased protein expression that leads to drug removal, mutations in drug binding sites, recovery of tumor protein production, and pre-existing genetic heterogeneity in tumor cell populations. In addition, the issue of drug resistance seems to have affected the development of new anticancer drugs. Drug resistance may be caused by various conditions, such as mutations, epigenetic modifications, and upregulation of drug efflux protein expression. Overcoming multidrug resistance in cancer treatment is becoming increasingly important. MCE designs a unique collection of 288 anti-drug-resistant compounds. It is a good tool to be used for research on cancer and other diseases.
Description & Advantages:
A unique collection of 288 anti-drug-resistant compounds for high throughput screening (HTS) and high content screening (HCS).
A useful tool for cancer and other diseases research.
Structurally diverse, medicinally active and cell permeable.
Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.
More detailed compound information with structure, IC50, and other chemical & biological data.
High purity and quality validated by NMR and LC/MS.
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• MCE (MedChemExpress) 拥有200 多种全球独家化合物库,我们致力于为全球科研客户提供前沿*全的高品质小分子活性化合物;
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热门标签:anti-drug-resistant