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Cytokine Inhibitors Library
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Cytokine Inhibitors Library
MCE 站:Cytokine Inhibitors Library
Cytokines are a kind of low molecular soluble proteins synthesized and secreted by immunogen, mitogen or other factors. They have functions of regulating innate and adaptive immune responses, promoting hematopoiesis, stimulating cell activation, proliferation and differentiation. The process of releasing a large number of cytokines is also called “Cytokine storm”, which can cause damage to many tissues and organs in the body. Cytokine is involved in the pathogenesis of many human diseases, including cancer, diabetes, chronic inflammatory diseases and so on. Cytokine inhibitors are a class of essential compounds that act by directly inhibiting the synthesis and release of cytokine or blocking the binding of cytokine to their receptors. Cytokine inhibitors are important compounds for the study of tumor and autoimmune diseases. MCE designs a unique collection of 964 cytokine inhibitors, mainly targeting the receptor interleukin (IL), colony-stimulating factor (CSF), interferon (IFN), tumor necrosis factor (TNF), growth factor (GF) and chemokine, which is an effective tool for development and research of anti-cancer, anti-chronic inflammatory diseases and anti-autoimmune diseases compounds.
Description & Advantages:
A unique collection of 964 cytokine inhibitors for high throughput screening (HTS) and high content screening (HCS).
The library contains compounds targeting the receptor interleukin (IL), colony-stimulating factor (CSF), interferon (IFN), tumor necrosis factor (TNF), growth factor (GF) and chemokine.
A useful tool for the discovery of anti-cancer, anti-chronic inflammatory diseases and anti-autoimmune diseases compounds
Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.
Structurally diverse, bioactive, and cell permeable.
More detailed compound information with structure, IC50, and other chemical & biological data.
High purity and quality validated by NMR and LC/MS.
All compounds are in stock and continuously updated.
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热门标签:cytokine