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Serine/Threonine Kinase Inhibitor Library

MCE 站：Serine/Threonine Kinase Inhibitor Library

Protein serine/threonine kinases (PSKs) are protein kinases that use ATP as a high-energy donor molecule to transfer phosphate groups to serine/threonine residues of target protein. As an important signal transduction regulator, serine/threonine kinases can affect the function of target proteins by disrupting enzyme activity or binding of target proteins to other proteins. Serine/threonine kinases are involved in the regulation of immune response, cell proliferation, differentiation, apoptosis ａnd other physiological processes. Serine/threonine kinase inhibitors are an important class of compounds that have been widely studied in cancer, chronic inflammation, autoimmune diseases, aging ａnd other diseases.MCE designs a unique collection of 1172 serine/threonine kinase inhibitors, mainly targeting the receptor PKA, Akt, PKC, MAPK/ERK, etc, which is an effective tool for development ａnd research of anti-cancer, anti-chronic inflammatory diseases, anti-autoimmune diseases ａnd anti-aging compounds.

Description & Advantages:

    A unique collection of 1172 serine/threonine kinase inhibitors for high throughput screening (HTS) ａnd high content screening (HCS).

   The library contains compounds targeting the receptor PKA, Akt, PKC, MAPK/ERK, etc.

   A useful tool for the discovery of anti-cancer, anti-chronic inflammatory diseases, anti-autoimmune diseases ａnd anti-aging compounds.

   Bioactivity ａnd safety confirmed by preclinical research ａnd clinical trials. Some have been approved by FDA.

   Structurally diverse, bioactive, ａnd cell permeable.

   More detailed compound information with structure, IC50, ａnd other chemical & biological data.

   High purity ａnd quality validated by NMR ａnd LC/MS.

   All compounds are in stock ａnd continuously updated.

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