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Oxytocin

CAS No. : 50-56-6

MCE 站：Oxytocin

产品活性：Oxytocin (α-Hypophamine; Oxytocic hormone) 是一种多效的下丘脑肽 (hypothalamic peptide)，有助于分娩、哺乳和亲社会行为。Oxytocin 可以作为一种压力应对分子，具有抗炎、抗氧化剂和保护作用，特别是在面对逆境或创伤时。

研究领域：GPCR/G Protein  |  Metabolic Enzyme/Protease

作用靶点：Oxytocin Receptor  |  Endogenous Metabolite

In Vivo: During the LMA task, rat core body temperature are modestly decreased.Oxytocin (subcutaneousinjection; 0.1mg/kg-0.3 mg/kg; single dose) produces significantly greater hypothermia (at 0.3 mg/kg) than either saline or the two lower doses of oxytocin. Oxytocin at 0.3mg/kg produces a significantly greater decrease in temperature than vehicle between 15-60min post injection, whereas 0.1mg/kg slightly decreases temperature at the 30min time point only.
Oxytocin (0.1mg/kg) engages in significantly more body sniffing ａnd ano-genital sniffing compared with saline controls. It also increases the total time spent in social interaction (71.6±4.3s), compared to those receiving vehicle (56.9±4.1s).

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