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YO-PRO-1/PI 细胞凋亡与坏死检测试剂盒

MCE 站：YO-PRO-1/PI 细胞凋亡与坏死检测试剂盒

MCE YO-PRO-1/PI 细胞凋亡与坏死检测试剂盒是一种基于 DNA 绿色荧光染料 YO-PRO-1 (YP1) 和 红色荧光染料碘化丙啶 (PI) 的双荧光法检测细胞凋亡和坏死的试剂盒。

Description & Advantages:

Apoptosis is a form of programmed cell death. Based on the cellular changes during programmed cell death, apoptosis is often classified into early, middle, ａnd later stages. The later stages of apoptosis are characterized by changes in nuclear morphology, chromatin condensation, nuclear envelope degradation, ａnd DNA fragmentation.

YO-PRO-1 (YP1), also known as Oxazole Yellow, is a non-cell-membrane-penetrating green fluorescent dye. It does not fluoresce without binding to DNA, but emits green fluorescence once bound to DNA. Propidium Iodide (PI) is a cell-membrane impermeable dye that can stain late-stage apoptosis cells ａnd necrosis cells with red fluorescence.

MCE YO-PRO-1/PI Apoptosis ａnd Necrosis Detection Kit is a dual-fluorescence method based on the green fluorescent dye YO-PRO-1 (YP1) ａnd the red fluorescent dye Propidium Iodide (PI) for detecting cell apoptosis ａnd necrosis. After co-staining with YO-PRO-1 ａnd PI, normal cells are essentially non-fluorescent, apoptosis cells show green fluorescence, ａnd necrosis cells show red ａnd green fluorescence.

This kit is compatible with various fluorescence detection systems, including fluorescence microscopy, flow cytometry, fluorescence enzyme labeling, ａnd other fluorescence detection systems.

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