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Vitamin D Receptor Antibody

MCE 站：Vitamin D Receptor Antibody

Vitamin D Receptor Antibody 是一个非偶联、分子量约 47 kDa、兔来源、抗 Vitamin D Receptor 多克隆抗体。Vitamin D Receptor Antibody 可用于：人、大鼠背景下 IHC-P, IHC-F, ICC, IF 实验，且不带标记。

Synonyms: Vitamin D3 receptor; 125 dihydroxyvitamin D3 receptor; 1 antibody 1,25-@dihydroxyvitamin D3 receptor; 125 dihydroxyvitamin D3 receptor; 25-dihydroxyvitamin D3 receptor; NR1I1; Nuclear receptor subfamily 1 group I member 1; VDR; VDR_HUMAN; Vitamin D (1,25- dihydroxyvitamin D3) receptor; Vitamin D hormone receptor; Vitamin D receptor; Vitamin D3 receptor,

研究背景：The related gene encodes vitamin D3 receptor, which is a member of the nuclear hormone receptor superfamily of ligand-inducible transcription factors. The receptor also functions as a receptor for the secondary bile acid, lithocholic acid. Downstream targets of vitamin D3 receptor are principally involved in mineral metabolism, though The receptor regulates a variety of other metabolic pathways, such as those involved in immune response ａnd cancer. Mutations in The related gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternatively spliced transcript variants encoding different isoforms have been described for The related gene. A recent study provided evidence for translational readthrough in The related gene, ａnd expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

基因 ID：7421

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