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TP1559LZiconotide Acetate (107452-89-1 free base)analgesic,non-opioid,Ziconotide Acetate (107452891 free
Ziconotide is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects.
价 格:¥电议型 号:TP1559L产 地:中国大陆
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T8439Clobenpropit dihydrobromideApoptosis,inhibit,Clobenpropit dihydrobromide,histamine H3R,antagonist,in
Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)
价 格:¥电议型 号:T8439产 地:中国大陆
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T6675Sodium Picosulfateinhibit,Inhibitor,Sodium Picosulfate
Sodium Picosulfate inhibits absorption of water and electrolytes, and increases their secretion.
价 格:¥电议型 号:T6675产 地:中国大陆
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T16940STAT5-IN-2STAT-5-IN-2,STAT5IN2,STAT5 IN 2
STAT5-IN-2 is an inhibitor of STAT5 with antileukemic effects (EC50s: 9 μM and 5 μM in K562 and KU812 cells, respectively).
价 格:¥电议型 号:T16940产 地:中国大陆
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TN12955-O-Caffeoylshikimic acidinhibit,5 O Caffeoylshikimic acid,Inhibitor,5OCaffeoylshikimic acid
5-O-Caffeoylshikimic acid shows anti-oxidative activity; it also shows anti-inflammatory activity, the underlying mechanism was associated with downregulation of nuclear factor-κB.
价 格:¥电议型 号:TN1295产 地:中国大陆
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PDK04236-METHYL-1H-INDOLE-2-CARBOXYLIC ACID6METHYL1HINDOLE2CARBOXYLICACID
价 格:¥电议型 号:PDK0423产 地:中国大陆
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TP1881L1Pep 2-8 ammonium salt(1541011-97-5 free base)Pep 2 8 ammonium salt(1541011 97 5 free base),Pep 28 am
Pep 2-8 ammonium salt is Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 μM). Restores LDL uptake in HepG2 cells treated with PCSK9.
价 格:¥电议型 号:TP1881L1产 地:中国大陆
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T22849ICI 199,441 hydrochlorideICI 199,441 hydrochloride
ICI 199,441 hydrochloride is a potent, selective agonist of κ-opioid receptor.
价 格:¥电议型 号:T22849产 地:中国大陆
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TQ0150LevcromakalimPotassium Channel,KcsA,Inhibitor,inhibit,BRL38227,BRL-38227,Levcromakalim
Levcromakalim is an activator of the ATP-sensitive K+ channel.
价 格:¥电议型 号:TQ0150产 地:中国大陆
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TP1789LMalantide acetate(86555-35-3 free base)Malantide acetate(86555 35 3 free base),Malantide acetate(865
Malantide acetate is a dodecapeptide phosphorylated by cyclic AMP-dependent protein kinase (PKA), and increases PKA activity.Malantide is a synthetic peptide that is phosphorylated by PKA and is used to measure PKA activity in vitro.
价 格:¥电议型 号:TP1789L产 地:中国大陆
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T16536Pimonidazole hydrochlorideinhibit,Pimonidazole hydrochloride,Pimonidazole,Inhibitor
Pimonidazole hydrochloride accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after the reduction of its nitro group. It can be used for qualitative and quantitative assessment of tumor hypoxia. Pimonidazole hydrochloride is a novel hypoxia marker for the complementary study of tumor hypoxia and cell proliferation in tumors.
价 格:¥电议型 号:T16536产 地:中国大陆
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TN1438beta-Amyrin acetateHMG-CoA,betaAmyrin acetate,LDL,Fungal,inhibit,Inhibitor,arthritic,hemolysis,antif
beta-Amyrin acetate inhibits HMG-CoA Reductase (HMGCR) and sEH activity with IC50 of 3.4 μM. beta-Amyrin acetate has anti-inflammatory, antifungal, antioxidant, and anti-hyperlipidemic activities.
价 格:¥电议型 号:TN1438产 地:中国大陆
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TN4871PyrolinPyrolin
Pyrolin has a strong antifungal activity and exerts a potent impact on the ultrastructure of M.fructicola.
价 格:¥电议型 号:TN4871产 地:中国大陆
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T61392NLRP3-IN-10
NLRP3-IN-10 is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading to suppress activation of NLRP3 inflammasome.
价 格:¥电议型 号:T61392产 地:中国大陆
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T9192BIIB068ADME,inhibit,FcγR,Autoimmune,Bruton tyrosine kinase,TNFα,BIIB 068,ROS,Inhibitor,reversible,Bt
BIIB068 is an selective, reversible and orally active BTK inhibitor (IC50 = 1 nM, Kd = 0.3 nM). BIIB068 is 400 times more selective for BTK than other kinases.
价 格:¥电议型 号:T9192产 地:中国大陆
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TP1898HS024selective,melanocortin,intake,Inhibitor,Melanocortin Receptor,MC Receptor,HS-024,food,HS024,inh
Highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks α-MSH- and MTII-induced hypotension and bradycardia in rats, following central administration in vivo.
价 格:¥电议型 号:TP1898产 地:中国大陆
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TN2079(-)-Pinoresinol()Pinoresinol,( ) Pinoresinol
(-)-Pinoresinol is isolated from the whole plant of Serissa japonica (Thunb.) Thunb.
价 格:¥电议型 号:TN2079产 地:中国大陆
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T7312AX20017AX 20017,AX20017,Inhibitor,Bacterial,inhibit,AX-20017
AX20017 is a small-molecule protein kinase G (PknG) inhibitor(IC50 : 0.39 μM). It acts by blocking the proliferation of M. tuberculosis.
价 格:¥电议型 号:T7312产 地:中国大陆