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T38622Bcl-xL antagonist 2Bcl xL antagonist 2,BclxL antagonist 2
Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM. Bcl-xL antagonist 2 induces apoptosis in cancer cells and can be used in studies about chronic lymphocytic leukemia and non-Hodgkin’s lymphoma.
价 格：￥电议型 号：T38622产 地：中国大陆
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T8656CAY10404Bcl-XL,CAY10404,cancer,COX,anti-inflammatory,Bcl-2,Apoptosis,Akt,H-1703,Cyclooxygenase,NSCLC
CAY10404 is a potent and highly selective inhibitor of COX-2 and COX-1. It is also a potent inhibitor of PKB/Akt and MAPK signalling pathways and induces apoptosis in NSCLC cells, with analgesic, anti-inflammatory and anti-cancer activities.
价 格：￥电议型 号：T8656产 地：中国大陆
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T80222TAT-BH4 (Bcl-xL) (TFA)；化合物 TAT-BH4 (Bcl-xL) (TFA)TAT-BH4 (Bcl-xL) (TFA)
"TAT-BH4 (Bcl-xL) TFA, primarily localized at the mitochondria, inhibits apoptotic cell death. This compound comprises an eosin-labeled cysteine at the N-terminal and the protein transduction domain from the HIV TAT protein (amino acids 49 to 57), fused to the Bcl-xL BH4 peptide. It is utilized in research concerning diseases associated with accelerated apoptosis [1]."
价 格：￥电议型 号：T80222产 地：中国大陆
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T80221TAT-BH4 (Bcl-xL)；化合物 TAT-BH4 (Bcl-xL)TAT-BH4 (Bcl-xL)
TAT-BH4 (Bcl-xL), primarily localized at the mitochondria, inhibits apoptotic cell death. This compound comprises an N-terminal eosin-labeled cysteine and the protein transduction domain of the HIV TAT protein (amino acids 49 to 57), fused to the Bcl-xL BH4 peptide. It serves as a tool for research into diseases characterized by accelerated apoptosis [1].
价 格：￥电议型 号：T80221产 地：中国大陆
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T74138PROTAC Bcl-xL degrader-2；化合物 PROTAC Bcl-xL degrader-2PROTAC Bcl-xL degrader-2
PROTAC Bcl-xL degrader-2, based on von Hippel-Lindau ligand, is a potent degrader of Bcl-xL (a Bcl-2 family member), demonstrating an IC 50 of 0.6 nM.
价 格：￥电议型 号：T74138产 地：中国大陆
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T74137PROTAC Bcl-xL ligand-1；化合物 PROTAC Bcl-xL ligand-1PROTAC Bcl-xL ligand-1
PROTAC Bcl-xL ligand-1 serves as a ligand targeting Bcl-xL, essential in synthesizing PROTACs [1].
价 格：￥电议型 号：T74137产 地：中国大陆
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T73999PROTAC Bcl-xL degrader-3；化合物 PROTAC Bcl-xL degrader-3PROTAC Bcl-xL degrader-3
PROTAC Bcl-xL degrader-3 is a potent ROTAC Bcl-xL degrader.
价 格：￥电议型 号：T73999产 地：中国大陆
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T73957PROTAC Bcl-xL degrader-1；化合物 PROTAC Bcl-xL degrader-1PROTAC Bcl-xL degrader-1
PROTAC Bcl-xL degrader-1 is a potent PROTAC composed of a Bcl-xL (Bcl-2 family member) ligand-binding group, a linker, and an IAP E3 ligases binding group, demonstrating effectiveness as a Bcl-xL degrader. It exhibits toxicity towards human platelets and MyLa 1929 cells, with IC50 values of 62 nM and 8.5 μM, respectively [1].
价 格：￥电议型 号：T73957产 地：中国大陆
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T38622Bcl-xL antagonist 2；Bcl-xL拮抗剂2Bcl-xL antagonist 2
Bcl-xL antagonist 2 is an effective and selective antagonist of Bcl-xL with an IC50 of 91 nM and a Ki of 65 nM. Bcl-xL antagonist 2 induces apoptosis in cancer cells and can be used in studies about chronic lymphocytic leukemia and non-Hodgkin’s lymphoma.
价 格：￥电议型 号：T38622产 地：中国大陆
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T10483Lisaftoclax；化合物LisaftoclaxBcl-2/Bcl-xl inhibitor 1|||APG-2575；Bcl-2/Bcl-xl inhibitor 1|||APG-2575
Lisaftoclax (Bcl-2/Bcl-xl inhibitor 1) is an oral dual inhibitor of Bcl-2 and Bcl-xl, with IC50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl, respectively. Lisaftoclax is used to treat chronic lymphocytic leukemia (CLL) by inhibiting the action of the BCL-2 protein, which promotes the death of leukemia cells.
价 格：￥电议型 号：T10483产 地：中国大陆
