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T3550X-376X-396;Ensartinib;恩沙替尼
Ensartinib (X-396) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inhibits ALK kinase, ALK fusion protei
价 格:¥电议型 号:T3550产 地:中国大陆
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T22324Ensartinib hydrochlorideEnsartinib dihydrochloride;X-396 dihydrochloride
Ensartinib dihydrochloride is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of known crizotinib-resistant ALK mutations. It potently inhibits both wild-type ALK and ALK variants (C1156Y, F1174, G1202R, L
价 格:¥电议型 号:T22324产 地:中国大陆
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T37585Ensartinib;Ensartinib (X-396)Ensartinib
Ensartinib (X-396) is a potent and dual ALK/MET inhibitor with IC50s of <0.4 nM and 0.74 nM, respectively.
价 格:¥电议型 号:T37585产 地:中国大陆
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T3550X-376;恩沙替尼Ensartinib|||X-396;Ensartinib|||X-396|||恩沙替尼
X-376 (Ensartinib) is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inhibits ALK kinase, ALK fusion proteins, and ALK point mutation variants. Inhibition of ALK leads to the disruption of ALK-mediated signaling and eventually inhibits tumor cell growth in ALK-expressing tumor cells. ALK belongs to the insulin receptor superfamily and plays an import
价 格:¥电议型 号:T3550产 地:中国大陆
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T22324Ensartinib hydrochloride;化合物Ensartinib (X-396) dihydrochlorideEnsartinib dihydrochloride|||X-396 dih
Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of known crizotinib-resistant ALK mutations. It potently inhibits both wild-type ALK and ALK variants (C1156Y, F1174, G1202R, L1196M, S1206R, and T1151 mutants) with in vitro IC50s of <4 nM.
价 格:¥电议型 号:T22324产 地:中国大陆