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T9041AES-350Histone deacetylases,AES 350,MV4-11,AES-350,Apoptosis,acute myeloid leukemia,AML,Inhibitor,in
AES-350 is a potent and orally active HDAC6 inhibitor(IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively). It is also against HDAC-3, -8, and -11 in an enzymatic activity assay with IC50 values of 0.187 μM, 0.245 μM, and >1μM, respectively. AES-350 triggers apoptosis in AML cells through HDAC inhibition and can be used for acute myeloid leukemia (AML) research.
价 格：￥电议型 号：T9041产 地：中国大陆
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T6908NSC 228155Epidermal growth factor receptor,Histone Acetyltransferase,EGFR,HER1,HATs,inhibit,Inhibito
NSC228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
价 格：￥电议型 号：T6908产 地：中国大陆
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T6695TasquinimodTasquinimod,ABR215050,Inhibitor,ABR 215050,inhibit,Histone deacetylases,HDAC
Tasquinimod is a quinoline-3-carboxamide linomide analog with antiangiogenic and potential antineoplastic activities. Tasquinimod has been shown to decrease blood vessel density but the exact mechanism of action is not known. This agent has also been shown to augment the antineoplastic effects of docetaxel and androgen ablation in a murine model of prostate cancer involving human prostate cancer xenografts.
价 格：￥电议型 号：T6695产 地：中国大陆
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T6668SGC-CBP30inhibit,IL-17A,HAT,HATs,BRD,Histone Acetyltransferase,ankylosing,SGCCBP30,cells,epigenetic,
SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).
价 格：￥电议型 号：T6668产 地：中国大陆
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TN1911MareinGLUT1,HDAC,Inhibitor,Akt,inhibit,antioxidative,Marein,Histone deacetylases,antihypertensive,AM
Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway, it may be a potent compound for preventing/counteracting diabetic encephalopathy.
价 格：￥电议型 号：TN1911产 地：中国大陆
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T7697BIX-01294PRMT1,recurrent,Autophagy,H3K9me3,Inhibitor,Cdkn1a,inhibit,p53,Gadd45a,MLKL,Histone Methylt
BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).
价 格：￥电议型 号：T7697产 地：中国大陆
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T7385WT-161Histone deacetylases,WT161,Inhibitor,inhibit,Apoptosis,WT-161,WT 161,HDAC
WT161 is a potent and selective inhibitor of HDAC6 (IC50:0.40 nM).
价 格：￥电议型 号：T7385产 地：中国大陆
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T6584MG 149HAT,Inhibitor,MG 149,Epigenetic Reader Domain,Apoptosis,HATs,inhibit,Histone Acetyltransferase
MG149 is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).
价 格：￥电议型 号：T6584产 地：中国大陆
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T8517BelinostatHistone deacetylases,PX-105684,PX 105684,Inhibitor,HDAC,Belinostat,PXD 101,inhibit,Autopha
Belinostat is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.
价 格：￥电议型 号：T8517产 地：中国大陆
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T9584UNC6934Inhibitor,UNC6934,Histone Methyltransferase,inhibit,UNC 6934,UNC-6934
UNC6934 is a chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2.
价 格：￥电议型 号：T9584产 地：中国大陆
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T8344CPTH2CPTH2,histone,Histone Acetyltransferase,Inhibitor,acetyltransferase,ccRCC,HAT,Gcn5p,CPTH 2,KAT3
CPTH2 is a histone acetyltransferase inhibitor modulating Gcn5 network.
价 格：￥电议型 号：T8344产 地：中国大陆
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TQ0050NCGC00244536NCGC 00244536,inhibit,Histone Demethylase,NCGC00244536,Inhibitor,NCGC-00244536
NCGC00244536 is a potent KDM4B inhibitor (IC50: 10 nM).
价 格：￥电议型 号：TQ0050产 地：中国大陆
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T9541CTBHATs,Inhibitor,neurons,CTB,Apoptosis,MCF-7 cell,cancer,potent,HAT,autophagic flux,inhibit,Histone
CTB (Cholera Toxin B subunit) is an activator of p300 histone acetyltransferase and induces apoptosis in MCF-7 cells.
价 格：￥电议型 号：T9541产 地：中国大陆
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T8233BRD3308β-cells,glucolipotoxicity,inflammatory,BRD-3308,Human immunodeficiency virus,BRD3308,Histone
BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.
价 格：￥电议型 号：T8233产 地：中国大陆
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T6389Anacardic AcidBacterial,HATs,inhibit,HAT,Anacardic Acid,Histone Acetyltransferase,Ginkgolic Acid C15
Anacardic Acid is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial activity, antibacterial activity, and inhibits prostaglandin synthase, lipoxygenase, and tyrosinase.
价 格：￥电议型 号：T6389产 地：中国大陆
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T6481DroxinostatHDAC3,hepatocellular carcinoma (HCC),Droxinostat,NS-41080,Apoptosis,Histone deacetylases,
Droxinostat is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.
价 格：￥电议型 号：T6481产 地：中国大陆
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T6639RG2833RGFP-109,RG2833,Inhibitor,RG 2833,RGFP 109,RG-2833,HDAC,inhibit,Histone deacetylases
RG2833 (RGFP109), a brain-penetrant HDAC inhibitor, is with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3, respectively.
价 格：￥电议型 号：T6639产 地：中国大陆
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T9243PFI-90antitumor,Inhibitor,PFI 90,differentiation,PAX3-FOXO1,demethylase,PFI-90,apoptosis,histone,His
PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action.PFI-90 has the potential for the antitumor activity. PFI-90 induces apoptosis and myogenic differentiation, resulting in the cell death increased.
价 格：￥电议型 号：T9243产 地：中国大陆
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T7378BRD9539Histone Methyltransferase,chromatin,PRC2,BRD9539,G9a,senescent,BRD-9539,BRD 9539,inhibit,H3K9
BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2), also known as G9a, with an IC50 value of 6.3 μM
价 格：￥电议型 号：T7378产 地：中国大陆
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T6847GSK-J1GSK-J1,inhibit,Inhibitor,Histone Demethylase,GSKJ1,GSK-J-1
GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively, >10-fold selectivity over other tested demethylases.
价 格：￥电议型 号：T6847产 地：中国大陆
