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T10773CF53CF-53,CF53
CF53 is a highly potent, selective and orally active inhibitor of BET protein, with a Ki of <1 nM, Kd of 2.2 nM and an IC50 of 2 nM for BRD4 BD1. CF53 binds to both the BD1 and BD2 domains of BRD2, BRD3, BRD4, and BRDT BET proteins with high affinities, very selective over non-BET bromodomain-containing proteins. CF53 shows potent anti-tumor activity both in vitro and in vivo.
价 格:¥电议型 号:T10773产 地:中国大陆
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T1766EmpagliflozinBI 10773;恩格列净
Empagliflozin is a Sodium-Glucose Cotransporter 2 Inhibitor. The mechanism of action of empagliflozin is as a Sodium-Glucose Transporter 2 Inhibitor.
价 格:¥电议型 号:T1766产 地:中国大陆
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T10773CF53CF53
CF53 is a highly potent, selective, and orally active inhibitor of BET protein (Ki: <1 nM, Kd: 2.2 nM, IC50: 2 nM for BRD4 BD1).
价 格:¥电议型 号:T10773产 地:美洲
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T1766EmpagliflozinEmpagliflozin,BI 10773,
Empagliflozin is a Sodium-Glucose Cotransporter 2 Inhibitor. The mechanism of action of empagliflozin is as a Sodium-Glucose Transporter 2 Inhibitor.
价 格:¥电议型 号:T1766产 地:美洲
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T36882CAY10773CAY10773CAY10773|||CAY-10773
CAY10773 is a derivative of the ferroptosis inducer sorafenib .1It selectively inhibits proliferation of BEL-7402, MGC803, and T24 bladder cancer cells (IC50s = 5.77, 5.21 and 3.97 μM, respectively) over non-cancerous HCV-29 cells (IC50= 23.19 μM). CAY10773 induces apoptosis in T24 cells when used at concentrations ranging from 2 to 6 μM but induces ferroptosis at concentrations greater than or equal to 6 μM with 10 hour or longer incubation times. It increases the production of reactive oxygen
价 格:¥电议型 号:T36882产 地:中国大陆
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T1766Empagliflozin恩格列净BI 10773|||恩格列净
Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with more than 300-fold selectivity for SGLT-1/4/5/6. Empagliflozin is used for the treatment of type 2 diabetes.
价 格:¥电议型 号:T1766产 地:中国大陆
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T10773CF53;化合物CF53CF53
CF53 is a highly potent, selective and orally active inhibitor of BET protein, with a Ki of <1 nM, Kd of 2.2 nM and an IC50 of 2 nM for BRD4 BD1. CF53 binds to both the BD1 and BD2 domains of BRD2, BRD3, BRD4, and BRDT BET proteins with high affinities, very selective over non-BET bromodomain-containing proteins. CF53 shows potent anti-tumor activity both in vitro and in vivo.
价 格:¥电议型 号:T10773产 地:中国大陆