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T10938D-Kynurenine
D-Kynurenine is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to mesenchyme. D-Kynurenine serves as a substrate in the fluorescence analysis of D-amino acid oxidase.
价 格:¥电议型 号:T10938产 地:中国大陆
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TQ0097AGN 193109AGN193109,Autophagy,Inhibitor,Retinoic acid receptors,Retinoid X receptors,RAR/RXR,AGN 193
AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).
价 格:¥电议型 号:TQ0097产 地:中国大陆
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T10927Cyt-PTPε Inhibitor-1
Cyt-PTPε Inhibitor-1 is an inhibitor of cytosolic protein tyrosine phosphatase ε. Cyt-PTPε Inhibitor-1 blocks the dephosphorylation of c-Src and exhibits anti-osteoclastic activity.
价 格:¥电议型 号:T10927产 地:中国大陆
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T10960Darbufelone
Darbufelone is a non-competitive dual inhibitor of PGF2α and LTB4. Dabfilon effectively inhibits PGHS-2 with a Ki of 10 μM and IC50s of 0.19 μM and 20 μM for PGHS-2 and PGHS-1.
价 格:¥电议型 号:T10960产 地:中国大陆
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T11092DPBQ
DPBQ is a p53 activator. DPBQ could activate p53 and trigger apoptosis in a polyploid-specific manner, without inhibition of topoisomerase or bind DNA.
价 格:¥电议型 号:T11092产 地:中国大陆
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T9109SSAA09E2domain,SARS-CoV,receptor,SSAA09E2,inhibit,SARS coronavirus,Inhibitor,spike,ACE2,binding,SSAA
SSAA09E2 is a new SARS-CoV replication inhibitor, acting by blocking early interactions of SARS-S with the receptor for SARS-CoV, Angiotensin Converting Enzyme-2 (ACE2).
价 格:¥电议型 号:T9109产 地:中国大陆
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T6639RG2833RGFP-109,RG2833,Inhibitor,RG 2833,RGFP 109,RG-2833,HDAC,inhibit,Histone deacetylases
RG2833 (RGFP109), a brain-penetrant HDAC inhibitor, is with IC50 of 60 nM and 50 nM for HDAC1 and HDAC3, respectively.
价 格:¥电议型 号:T6639产 地:中国大陆
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T10923CYP17-IN-1CYP17IN1,CYP17 IN 1,CYP-17-IN-1
CYP17-IN-1 is an effective oral inhibitor of CYP17 that can inhibit CYP17 in rats and humans with IC50 of 15.8 and 20.1 nM.
价 格:¥电议型 号:T10923产 地:中国大陆
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T8109d-Neomenthold Neomenthol,dNeomenthol
d-Neomenthol is a natural product.
价 格:¥电议型 号:T8109产 地:中国大陆
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T10980DCPLA-ME
DCPLA-ME is the methyl ester form of DCPLA and can be used to treat neurodegenerative diseases. It is an effective PKCε activator.
价 格:¥电议型 号:T10980产 地:中国大陆
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T10903CWHM-1552CWHM1552,CWHM 1552
CWHM-1552 is an effective Plasmodium falciparum inhibitor. For the 3D7 and Dd2 strains, the IC50s are 51 nM and 53 nM.
价 格:¥电议型 号:T10903产 地:中国大陆
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T10964DB1976DB1976,DB-1976
DB1976 is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. DB1976 potently inhibits PU.1 binding (IC50 of 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-λB affinity, KD of 12 nM) in vitro. DB1976 has Apoptosis-inducing effect.
价 格:¥电议型 号:T10964产 地:中国大陆
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T27696JTK-109JTK 109
JTK-109 is an inhibitor of hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor and inhibits G1b and G3a subgenomic replicons and recombinant enzymes.
价 格:¥电议型 号:T27696产 地:中国大陆
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TP1092Myelin Basic Protein (MBP) (68-82), guinea pigMyelin Basic Protein (MBP) (68-82), guinea pig,Inhibit
Myelin Basic Protein (68-82), guinea pig, is a peptide with the sequence Tyr-Gly-Ser-Leu-Pro-Gln-Lys-Ser-Gln-Arg-Ser-Gln-Asp-Glu-Asn.Myelin Basic Protein (MBP) (68-82), guinea pig is a fragment of myelin basic protein (MBP).
价 格:¥电议型 号:TP1092产 地:中国大陆
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T10954DAGLβ-IN-1DAGLβIN1,DAGLβ IN 1
DAGLβ-IN-1 is a universal intermediate for designing DAGL tailored activity-based probes, and is an inhibitor of diacylglycerol lipase-β (DAGLβ).
价 格:¥电议型 号:T10954产 地:中国大陆
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TP2131LRac1 Inhibitor W56 acetate(1095179-01-3 free base)Rac1 Inhibitor W56 acetate(1095179013 free base),R
Peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with Rac1-specific GEFs TrioN, GEF-H1 and Tiam1.
价 格:¥电议型 号:TP2131L产 地:中国大陆
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T10936D-I03
D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 ?M. D-I03 specifically inhibits RAD52-dependent single-chain annealing (SSA) and D-loop formation, with IC50 of 5 ?M and 8 ?M, respectively. D-I03 inhibited the growth of BRCA1 and BRCA2 deficient cells and inhibited the formation of damage-induced RAD52 foci, but does not effect on RAD51 foci induced by Cisplatin.
价 格:¥电议型 号:T10936产 地:中国大陆
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T10965DBPR112DBPR-112,DBPR112
DBPR112 is an orally active furanopyrimidine-based EGFR inhibitor with IC50s of 15 nM and 48 nM for EGFRWT and EGFRL858R/T790M, respectively. DBPR112 can occupy the ATP-binding site. DBPR112 has significant antitumor efficacy.
价 格:¥电议型 号:T10965产 地:中国大陆