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T9589SI-113SI113,SI 113
SI-113 is a potent and selective inhibitor of SGK1, a serine/threonine protein kinase, that modulates several oncogenic signaling cascades.
价 格:¥电议型 号:T9589产 地:中国大陆
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T40229SR-0813SR0813,SR 0813
SR-0813 is a potent and selective ENL/AF9 YEATS domain inhibitor. SR-0813 has IC 50 and EC 50 values of 25 nM and 205 nM for ENL YEATS domain, respectively. SR-0813 has IC 50 and EC 50 values of 311 nM and 76 nM (CETSA) for AF9 YEATS domain, respectively. SR-0813 binds MAP3K19 with over 100-fold lower affinity ( K d =3.5 μM) than ENL YEATS ( K d =30 nM). SR-0813 can be used for the research of acute leukemia.
价 格:¥电议型 号:T40229产 地:中国大陆
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T12943SNDX-5613SNDX-5613
SNDX-5613 is a potent and specific inhibitor of Menin-MLL(Ki of 0.149 nM and a cell based IC50 of 10-20 nM). SNDX-5613 can be used for the research of MLL-rearranged (MLL-r) acute leukemias.
价 格:¥电议型 号:T12943产 地:美洲
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T13882SCH00013SCH00013
SCH00013 is an agent of cardiotonic that primarily acts via an increase in myofibrillar Ca++ sensitivity. SCH00013 have a significant Ca(2+)sensitizing effect at pH 7.2 to 7.4.
价 格:¥电议型 号:T13882产 地:美洲
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T8344217(13→14)-Abeo-ent-3S*,13S*,16-trihydroxystrob-8(15)-ene;化合物 17(13→14)-Abeo-ent-3S*,13S*,16-trihydro
17(13→14)-Abeo-ent-3S*,13S*,16-trihydroxystrob-8(15)-ene is a sesquiterpene lactone of natural origin that exhibits anti-inflammatory properties [1].
价 格:¥电议型 号:T83442产 地:中国大陆
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T81151SK-MLCK M13;化合物 SK-MLCK M13SK-MLCK M13
SK-MLCK M13 is a biologically active peptide representing the calmodulin (CaM)-binding domain of CaM target proteins, where CaM is a ubiquitous Ca2+ binding protein.
价 格:¥电议型 号:T81151产 地:中国大陆
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T7945SU14813;化合物SU14813SU14813
SU14813 is a multi-receptor tyrosine kinase inhibitor with potent antiangiogenesis and antitumor activity (IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRβ and KIT).
价 格:¥电议型 号:T7945产 地:中国大陆
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T78694SHP2-IN-13;化合物 SHP2-IN-13SHP2-IN-13
SHP2-IN-13 is an orally active, highly selective allosteric inhibitor targeting the SHP2 “tunnel site,” exhibiting an IC50 of 83.0 nM. It holds potential for research into cancers with RTK oncogenic drivers and diseases associated with SHP2.
价 格:¥电议型 号:T78694产 地:中国大陆
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T75182GK13S;化合物 GK13SGK13S
G13KS is a deubiquitinase UCHL1 ligand and inhibitor. G13KS inhibits recombinant and cellular UCHL1. G13KS reduces levels of monoubiquitin in human glioblastoma cells [1] .
价 格:¥电议型 号:T75182产 地:中国大陆
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T74807SARS-CoV-2 3CLpro-IN-13;化合物 SARS-CoV-2 3CLpro-IN-13SARS-CoV-2 3CLpro-IN-13
SARS-CoV-2 3CLpro-IN-13 is a potent inhibitor of the SARS-CoV-2 3CL protease, demonstrating significant anti-coronavirus activity with an IC50 value of 21 nM [1].
价 格:¥电议型 号:T74807产 地:中国大陆
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T74268STING agonist-13;化合物 STING agonist-13STING agonist-13
STING Agonist-13, a stimulator of interferon genes (STING) agonist, enhances cancer immunity through STING-mediated immune activation. It activates STING downstream signaling to promote type I interferon immune responses, significantly reduces tumor volume, and exhibits immunological memory-derived cancer inhibition [1].
价 格:¥电议型 号:T74268产 地:中国大陆
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T71295SOR-C13;化合物 SOR-C13SOR-C13
SOR-C13 is an inhibitor of transient receptor potential cation channel vanilloid family member 6 (TRPV6, CaT1 or CATL) with potential antineoplastic activity. TRPV6 calcium channel inhibitor SOR-C13 binds to TRPV6 and prevents the influx of calcium ions into TRPV6-expressing tumor cells. This inhibits the activation of nuclear factor of activated T-cell (NFAT) transcription complex which may result in an inhibition of calcium-dependent cancer cell proliferation and an induction of apoptosis in t
价 格:¥电议型 号:T71295产 地:中国大陆
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T70948Sjc 13;化合物 Sjc 13Sjc 13
Sjc 13 is an azaindolidine derivative that is a cell adhesion molecule inhibitor.
价 格:¥电议型 号:T70948产 地:中国大陆
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T66315(7R,8R,9S,13S,14S,17S)-7-(9-Bromononyl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta
(7R,8R,9S,13S,14S,17S)-7-(9-Bromononyl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol is a useful organic compound for research related to life sciences. The catalog number is T66315 and the CAS number is 875573-67-4.
价 格:¥电议型 号:T66315产 地:中国大陆
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T66301(3S,8R,9S,10R,13S,14S)-17-Iodo-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopent
(3S,8R,9S,10R,13S,14S)-17-Iodo-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol is a useful organic compound for research related to life sciences. The catalog number is T66301 and the CAS number is 32138-69-5.
价 格:¥电议型 号:T66301产 地:中国大陆
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T65148Estradiene dione-3-keta;化合物 (8S,13S,14S)-13-Methyl-1,2,6,7,8,12,13,14,15,16-decahydrospiro[cyclopent
Estradiene dione-3-keta is a useful organic compound for research related to life sciences. The catalog number is T65148 and the CAS number is 5571-36-8.
价 格:¥电议型 号:T65148产 地:中国大陆
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T64990(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-10,13-Dimethyl-2,16-di(piperidin-1-yl)hexadecahydro-1H-cyclopen
(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-10,13-Dimethyl-2,16-di(piperidin-1-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol is a useful organic compound for research related to life sciences. The catalog number is T64990 and the CAS number is 13522-16-2.
价 格:¥电议型 号:T64990产 地:中国大陆
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T643936-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-
6-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxo-1H-pyridine-3,4-dicarbonitrile is a biologically active compound, which is utilized for research in the fields of chemistry and life sciences.
价 格:¥电议型 号:T64393产 地:中国大陆
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T62722SC13;化合物 SC13SC13
SC13, a novel mitragynine analog, exhibits low-efficacy agonism at Mu opioid receptors and provides antinociception while minimizing adverse effects.
价 格:¥电议型 号:T62722产 地:中国大陆
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T62591SBE13;化合物 SBE13SBE13
SBE13 is a selective and potent inhibitor of Plk1 (IC50: 200 pM). SBE13 has a weak effect on Plk2 or Plk3 with IC50 values of >66 μM and 875 nM respectively.
价 格:¥电议型 号:T62591产 地:中国大陆