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  • T7858215-keto-Prostaglandin E2；化合物 15-keto-Prostaglandin E215-keto-PGE2；15-keto-PGE2

    15-keto-Prostaglandin E2, an endogenous metabolite, inhibits STAT3 activation through binding to Cys259 and regulates breast cancer cell growth and progression. Additionally, it binds and stabilizes the EP2 and EP4 receptors, activates PPAR-γ, and promotes fungal growth [1] [2] [3].

    价 格：￥电议型 号：T78582产 地：中国大陆

  • T3799115-keto Prostaglandin F2α；化合物15-keto Prostaglandin F2α15-keto Prostaglandin F2α|||15-keto PGF2α；15-k

    15-keto Prostaglandin F2α is a metabolite of Prostaglandin F2α that lowers intraocular pressure in rabbits.

    价 格：￥电议型 号：T37991产 地：中国大陆

  • T3799015-keto Prostaglandin F1α；15-keto Prostaglandin F1α15-keto Prostaglandin F1α；15-keto Prostaglandin F

    15-keto PGF1α is the initial metabolite of PGF1α via 15-hydroxy PGDH. In mammals, oxidation of C-15 markedly attenuates receptor binding and activity. In fish, the 15-keto compounds serve as post-ovulatory pheromones and are more active than the parent prostaglandins.

    价 格：￥电议型 号：T37990产 地：中国大陆

  • T3793415-keto-17-phenyl trinor Prostaglandin F2α；15-keto-17-phenyl trinor Prostaglandin F2α15-keto-17-phen

    Bimatoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group and amide hydrolysis of Bimatoprost produces 15-keto-17-phenyl trinor PGF2α. 15-keto-17-phenyl trinor PGF2α is a potential metabolite of bimatoprost when administered to animals. 15-keto PG analogs are potential minor impurities in commercial preparations of their corresponding bulk drug compounds. Although much less potent that the parent compo

    价 格：￥电议型 号：T37934产 地：中国大陆

  • T3793315-keto Latanoprost (free acid)；15-keto Latanoprost (free acid)15-keto Latanoprost (free acid)

    15-keto Latanoprost is a potential metabolite of latanoprost when administered to animals. 15-keto Latanoprost is also one of the common minor impurities found in commercial preparations of the bulk drug compound. Although much less potent that the parent compound latanoprost, 15-keto latanoprost still retains the ability to produce a small but measurable decrease (1 mm Hg) in the intraocular pressure of normal cynomolgus monkeys when administered at a dose of 1 μg/eye. 15-keto Latanoprost is al

    价 格：￥电议型 号：T37933产 地：中国大陆

  • T3793215-keto Latanoprost；15-keto Latanoprost15-keto Latanoprost

    Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group without isopropyl ester hydrolysis produces 15-keto latanoprost. 15-keto Latanoprost is a potential metabolite of latanoprost when administered to animals. 15-keto Latanoprost is also one of the common minor impurities found in commercial preparations of the bulk drug compound. Although much less potent that the parent compound latanoprost, 15-k

    价 格：￥电议型 号：T37932产 地：中国大陆

  • T3725713,14-dihydro-15-keto Prostaglandin D1；13,14-dihydro-15-keto Prostaglandin D113,14-dihydro-15-keto P

    Prostaglandin D1 (PGD1) is the theoretical D-series metabolite of dihomo-γ-linolenic acid (DGLA), but to date it has not been isolated as a natural product. It is an inhibitor of ADP-induced platelet aggregation in humans with an IC50 value of 320 ng/ml, about 1/10 as potent as PGD2. 13,14-dihydro-15-keto Prostaglandin D1 (13,14-dihydro-15-keto PGD1) is the theoretical metabolite of PGD1 via the 15-hydroxy PG dehydrogenase metabolic pathway. No biological studies for this compound have been repo

    价 格：￥电议型 号：T37257产 地：中国大陆

  • T3621015-keto Treprostinil (sodium salt)；15-keto Treprostinil (sodium salt)15-keto Treprostinil (sodium sa

    15-keto Treprostinil is an impurity found in treprostinil , which is a stable analog of prostaglandin I2 with a longer plasma half-life. Formulations containing treprostinil are used for the treatment of primary pulmonary hypertension.

    价 格：￥电议型 号：T36210产 地：中国大陆

  • T3620915-keto Prostaglandin A1；15-keto Prostaglandin A115-keto Prostaglandin A1；15-keto Prostaglandin A1

    Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. 15-keto PGA1 is a metabolite of PGA1, produced by 15-hydroxy PG dehydrogenase. It can be produced from PGA1 in pig lung, trachea, aorta, and pulmonary artery tissue preparations. 15-keto PGA1, given at a concentration of 6 μM, causes vasoconstriction of rabbit lung that is comparable to that induced by angiotensin II.

    价 格：￥电议型 号：T36209产 地：中国大陆

  • T361678-iso-15-keto Prostaglandin F2β；8-iso-15-keto Prostaglandin F2β8-iso-15-keto Prostaglandin F2β；8-iso

    8-iso Prostaglandin F2β (8-iso PGF2β) is an isomer of PGF2α of non-enzymatic origin. It is one of 64 possible isomers of PGF2α which can be produced by free radical peroxidation of arachidonic acid. 8-iso PGF2β exhibits very weak contraction of human umbilical vein artery and does not promote aggregation of human whole blood. However, 8-iso PGF2β moderately contracts both the canine and porcine pulmonary vein, although the effect is much weaker than that exhibited by other isoprostanes such as 8

    价 格：￥电议型 号：T36167产 地：中国大陆

  • T361668-iso-15-keto Prostaglandin F2α；8-iso-15-keto Prostaglandin F2α8-iso-15-keto Prostaglandin F2α；8-iso

    8-iso-15-keto Prostaglandin F2α (8-iso-15-keto PGF2α) is a metabolite of the isoprostane 8-iso PGF2α in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2α) is a prostaglandin-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-iso PGF2α is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation. A similar pattern is observed when tritiated 8-iso PGF2α is infused into rabbits. Early in the in

    价 格：￥电议型 号：T36166产 地：中国大陆

  • T361658-iso-13,14-dihydro-15-keto Prostaglandin F2α；8-iso-13,14-dihydro-15-keto Prostaglandin F2α8-iso-13,

    8-iso-13,14-dihydro-15-keto Prostaglandin F2α (8-iso-13,14-dihydro-15-keto PGF2α) is a metabolite of the isoprostane, 8-isoprostane (8-iso PGF2α), in rabbits, monkeys and humans. 8-iso PGF2α is a PG-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-isoprostane is converted primarily to metabolites having 2 or 4 carbon atoms removed from the top side chain by β-oxidation. A similar pattern is observed when tritiated 8-isoprostane is infused into ra

    价 格：￥电议型 号：T36165产 地：中国大陆

  • T3614813,14-dihydro-15-keto Prostaglandin F1α；13,14-dihydro-15-keto Prostaglandin F1α13,14-dihydro-15-keto

    13,14-dihydro-15-keto Prostaglandin F1α (13,14-dihydro-15-keto PGF1α) is a metabolite of PGF1α that has been reported in the rat stomach. The measurement of 13,14-dihydro-15-keto PGF1α can be used as a marker of the in vivo production of PGF1α.

    价 格：￥电议型 号：T36148产 地：中国大陆

  • T3614713,14-dihydro-15-keto Prostaglandin E1；13,14-dihydro-15-keto Prostaglandin E113,14-dihydro-15-keto P

    13,14-dihydro-15-keto Prostaglandin E1 inhibits ADP-induced platelet aggregation in human isolated platelet-rich plasma (IC50=14.8 μg/mL) and is a PGE1 metabolite.

    价 格：￥电议型 号：T36147产 地：中国大陆

  • T3594415-keto-17-phenyl trinor Prostaglandin F2α ethyl amide；15-keto-17-phenyl trinor Prostaglandin F2α et

    Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2α ethyl amide (17-phenyl trinor PGF2α ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group produces 15-keto-17-phenyl trinor PGF2α ethyl amide. 15-keto-17-phenyl trinor PGF2α ethyl amide is a potential metabolite of 17-phenyl trinor PGF2α ethyl amide when 17-phenyl trinor PGF2α ethyl amide is administered to intact animals. No pharmacologi

    价 格：￥电议型 号：T35944产 地：中国大陆

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