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T15641K777
K777 is a potent, orally active and irreversible inhibitor of cysteine protease. K777 is a potent CYP3A4 inhibitor (IC50= 60 nM). K777 is also a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 irreversibly inhibits Cruzain, which is the major cysteine protease of Trypansoma cruzi, and cathepsins B and L. K777 targets cathepsin-mediated cell entry and wxibits a broad-spectrum antiviral activity. K777 inhibits EBOV and SARS-CoV pseudovirus entry with IC50 values of 0.87
价 格:¥电议型 号:T15641产 地:中国大陆
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TN1569DeoxylapacholDeoxylapachol,Fungal,inhibit,Inhibitor
Deoxylapachol has anti-wood rot activity, it can inhibit the brown rot fungi Gloeophyllum sepiarium CBS 353.74 and Gloeophyllum trabeum CBS 318.50 and the white rot fungi Merulius tremellosus CBS 280.73 and Phlebia brevispora CBS 509.92. It also can induce fungal cell wall stress.
价 格:¥电议型 号:TN1569产 地:中国大陆
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T7295MiridesapGSK 2315698,GSK-2315698,Miridesap,Inhibitor,inhibit
Miridesap is a divalent crosslinker of SAP that causes rapid depletion of circulating SAP via hepatic clearance. It also produces significant reduction of SAP from cerebrospinal fluid and visceral amyloid deposits
价 格:¥电议型 号:T7295产 地:中国大陆
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TP1563Gap19myocardial,Gap19,cytoplasmic,Cx40/pannexin-1,inhibit,Gap Junction Protein,C-terminus,Gap 19,hem
Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.
价 格:¥电议型 号:TP1563产 地:中国大陆
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T7839Lasofoxifene Tartrateosteoporosis,inhibit,Estrogen Receptor/ERR,arthritis,CP 336156,endocrine resist
Lasofoxifene Tartrate is a third-generation, non-steroidal selective estrogen receptor modulator.
价 格:¥电议型 号:T7839产 地:中国大陆
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T8532IM156IM-156,IM156
IM156 (HL156A; HL271 acetate) is a chemical derivative of Metformin. IM156 is a potent and orally active AMPK activator that increases AMPK phosphorylation. IM156 attenuates aging-associated cognitive impairment in animal model [1] [2]. IM156 is a potent oxidative phosphorylation (OXPHOS) inhibitor which is able to be used for the research of solid tumors [3].
价 格:¥电议型 号:T8532产 地:中国大陆
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T15612JH-VIII-157-02CD246,Cluster of differentiation 246,inhibit,Anaplastic lymphoma kinase,Anaplastic lym
JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-ALKwt, EML4-ALK C1156Y, EML4-ALK F1174L, and EML4-ALK F1174L.
价 格:¥电议型 号:T15612产 地:中国大陆
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T60156PBRM1-BD2-IN-2PBRM1BD2IN2
PBRM1-BD2-IN-2 is a selective and cell-active polybromo-1 (PBRM1) bromodomain inhibitor. PBRM1-BD2-IN-2 has binding affinity and inhibitory activity for PBRM1-BD2 with Kd and IC50 values of 9.3 μM and 1.0 μM, respectively. PBRM1-BD2-IN-2 can be used for the research of cancer.
价 格:¥电议型 号:T60156产 地:中国大陆
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T15608Jarin-1Jarin 1,Jarin1
Jarin-1 is a jasmonic acid-amido synthetase (JAR1) inhibitor (IC50: 3.8 μM). Jarin-1 specific suppresses bioactive JA biosynthesis in Arabidopsis and other plants.
价 格:¥电议型 号:T15608产 地:中国大陆
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T15615JND3229JND-3229,JND3229
JND3229 is a reversible EGFRC797S inhibitor with IC50 values of 5.8, 6.8 and 30.5 nM for EGFRL858R/T790M/C797S, EGFRWT and EGFRL858R/T790M, respectively. JND3229 has good anti-proliferative activity and can effectively inhibit tumour growth in vivo. JND3229 can be used in cancer research, especially in non-small cell carcinoma.
价 格:¥电议型 号:T15615产 地:中国大陆
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TP1561123C4Inhibitor,123C-4,123C4,Ephrin Receptor,inhibit
123C4 is a potent, selective and competitive agonist of the receptor tyrosine kinase?EPHA4 (Ki=0.65 μM)[1].
价 格:¥电议型 号:TP1561产 地:中国大陆
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TP1543LG280-9 acetate(156761-76-1 free base)G280 9 acetate(156761 76 1 free base),G-280-9 acetate(156761-76
G280-9 acetate is a common melanoma gp100 epitope restricted by MHC-associated HLA-A2. The G280-9 sequence is unique because it could be recognized by cytotoxic T lymphocytes at very low concentrations, however it shows low total immunogenicity that may be attributable to relatively low affinity of this peptide for the HLA-A2.
价 格:¥电议型 号:TP1543L产 地:中国大陆
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TN1563Dehydropachymic acidAutophagy,inhibit,Inhibitor,Dehydropachymic acid
Dehydropachymic acid shows antiinflammatory activity.
价 格:¥电议型 号:TN1563产 地:中国大陆
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T15648KDM5-C70KDM5-C49,Histone Demethylase,JARID1,retinoblastoma,inhibit,KDM5 C70,KDM5-C70,KDM-5-C70,phosp
KDM5-C70 is an ethyl ester derivative of KDM5-C49. KDM5-C70 is an effective, cell-permeable, and pan-KDM5 histone demethylase inhibitor. KDM5-C70 has an antiproliferative effect in myeloma cells, inducing a genome-wide elevation of H3K4me3 levels.
价 格:¥电议型 号:T15648产 地:中国大陆
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TP1843LSystemin acetate(137181-56-7 free base)Systemin acetate(137181567 free base),Systemin acetate(137181
Systemin acetate is an 18-amino acid polypeptide with the sequence AVQSKPPSKRDPPKMQTD that is found in Solanaceae plants (such as tomato and potato).
价 格:¥电议型 号:TP1843L产 地:中国大陆
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TP1267LCEF27, Epstein-Barr Virus BRLF-1 lytic 148-156 acetateCEF27, EpsteinBarr Virus BRLF1 lytic 148156 ac
CEF27, Epstein-Barr Virus BRLF-1 lytic 148-156 acetate corresponding to amino acids 148-156 of the BRLF1. BRLF1 is a transcriptional activator that binds directly to a GC-rich motif present in some Epstein-Barr virus (EBV) lytic gene promoters.
价 格:¥电议型 号:TP1267L产 地:中国大陆
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T61156L-Lysyl-L-lysine dihydrochloride
L-Lysyl-L-lysine dihydrochloride is an enzyme cleavable linker. L-Lysyl-L-lysine dihydrochloride can be used as facile linker for delivering multiple biologically active peptides.
价 格:¥电议型 号:T61156产 地:中国大陆
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T15614JJKK 048inhibit,JJKK-048,JJKK048,MAGL,Inhibitor,Monoacylglycerol lipase,JJKK 048
JJKK 048 is a potent and selective MAGL inhibitor.
价 格:¥电议型 号:T15614产 地:中国大陆
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T7156NIBR189Inhibitor,mice,small molecule,NIBR 189,autoimmune diseases,autoimmune,EBI2/GPR183,NIBR189,U93
NIBR189 is a potent and selective antagonist of EBI2 (GPR183) receptor (IC50 of 11 and 15 nM for human and mouse EBI2 receptors, respectively)
价 格:¥电议型 号:T7156产 地:中国大陆
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TWS1563IncensoleInhibitor,inhibit,Incensole
1. Incensole has a protective or stimulating effect on β-cells of the rat pancreas, it also can increase the insulin secretion, which evidenced by a significant increase both in body weight and in liver glycogen.
价 格:¥电议型 号:TWS1563产 地:中国大陆